leukemia Flashcards
acute myeloid leukemia (AML) is common in what age group
adults
acute lymphoblastic leukemia (ALL) is common in what age group
children
common side effect of AML
DIC
leukemia
neoplasia within the hemopoietic stem cell pathway
acute promyelocyte leukemia has what translocation?
(15;17)
ALL has what common markers?
CD10, CD19 and TdT
AML is commonly know to have what on the peripheral smear?
auer rods
treatment for acute promyelocyte leukemia ?
ATRA
all trans retinoic acid + arsenic
what translocation is a bad prognosis cytogenetic marker for ALL?
(9;22)
what is a good prognosis cytogenetic marker for ALL?
(12,21)
what is a bad prognosis comorbity for ALL?
down syndrome
What is the common finding for hemoglobin, platelet, and neutrophil and leukocyte count for acute leukemia?
anemia, neutropenia, thrombocytopenia, and leukocytosis
acute myeloid leukemia arrests cells in what stage?
myeloblast
ALL arrest cells in what stage?
lymphoblast pre-b and pre-t cells
B-Cell/T-cell ALL has a worse prognosis?
T-cell