USMLE rx II Flashcards
aminocaproic acid
used to reverse the effects of tPA tissue plasminogen activator
when administrating heparin what three tests do you need to monitor
- platelet (to monitor for HIT) 2. aTTP 3. PFA 100
von willebrands
- FVIII and adhesion of platelets to collagen via glycoproteins - slightly increased or normal aPTT
protein C inactivates _____ and ____ factors
V and VIII
deficiency in protein C would lead to
coagualtion thrombosis
a symptom of transfusion error can be hypocalcemia … which test would let you know if this was the transfusion problem and what symptoms would be present
- fatigue, irritability, muscle pain, tingling sensation around the mouth - chvostek test- tapping the facial nerve just close to the ear causes intense pain
the most common inherited form of thrombophilia that could cause DVT
factor V leiden mutation meaning the coagulation cascade is not inhibited and clot formation occurs more readily
babies have to receive vitmain K right when they are born to prevent
vitamin K deficiency
vitamin K deficiency in newborns causes what tests to prolong
PT and aPTT
vitamin K deficiency causes what symptoms
increases risks of hemorrhage GI, umbilical, etc
c- vitain K deficiency
patients with HIT should eb started on
agratroban a direct inhibitor of thrombin
DVT and decreasing the likilhood of a recurrence
QUIT SMOKING
acute graft rejection is a potential side effect of solid organ transplant and is mediated by recipients cytotxic t - cells. In comparsion what occurs with bone marrow transplant?
alloreactive donor T lymphocytes
vitamin K deficiency can be due to what antibiotic?
ceftriaxone /cephlasporin and can cause prolonged PT and PTT
