genetics Flashcards
1
Q
allelic heterogeneity
A
different alleles (variants) of the same gene can lead to the same phenotype; can order one panel
2
Q
locus heterogeneity
A
there may be several different locations or locus’s for different genes; clinically relevant because may need to order several different genetic marker tests because there are different genes responsible
3
Q
variable expressivity
A
the components or severity of a phenotype for a given condition may vary among individuals
4
Q
faconis anemia is known to be caused by at least 15 genes what genetic concept does this illustrate?
A
locus heterogeneity
5
Q
alleles
A
different versions of a gene
6
Q
locus
A
location of gene
7
Q
founder effect and genetic drift
A
this results in higher carrier frequencies in certain populations
