Lesson 1-4 Physio Ex Flashcards

1
Q

What is the resting membrane potential of a neuron caused by?

A

the electrochemical gradient of ions Na+ and K+

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

T/F: Alterations to the ion concentration inside or outside of the neuron will alter the resting membrane potential.

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Increasing extracellular [K+] causes the membrane potential to do what?

A

go from -70mV to -40mV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

increasing extracellular [Na+] causes the membrane potential to do what?

A

drop from -70mV to -72mV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is indicated by the greater change of the resting potential when [K+] is changed than when the [Na+] is changed?

A

there are more passive K+ channels than passive Na+ channels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What maintains the difference in concentration of K+ and Na+ inside/outside the cell?

A

the Na+/K+ pump, without it the leak channels would eventually bring the potential to 0

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

decreasing the extracellular [Na+] will cause what?

A

the membrane potential to become more negative since less Na+ will enter the cell via Na+ channels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

increasing the extracellular [K+] will cause what?

A

the membrane potential to become less negative since less K+ will leave the cell via passive K+ channels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

If the correct stimulus is applied to a sensory receptor will cause it to…

A

open or close membrane ion channels aka sensory transduction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

opening or closing ino channels with produce a _____ _____ that may be either depolarizing or hyperpolarizing

A

graded (local) potential

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What do Pacinian corpuscles respond to?

A

ranges of pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What do Pacinian corpuscles NOT respond to?

A

chemicals, heat, or light stimuli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Olfactory receptors respond to?

A

ranges of chemical stimulus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are olfactory receptors NOT responsive to?

A

pressure, heat, and light

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

T/F: free nerve ending can respond to multiple modalities of stimuli

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What can free nerve endings respond to?

A

ranges of heat and pressure

17
Q

What is one reason free nerve endings can respond to multiple types of stimuli?

A

They are involved in detecting different types of excessive stimuli that will be perceived as pain

18
Q

a stimulus voltage of _____ and above elicited an action potential in the nerve

A

20mV

19
Q

Did increasing the voltage affect the speed or strength of the action potential?

A

no

20
Q

Why was there no decrease in the magnitude of the action potential between R1 and R2?

A

the action potential is regenerated at each segment of axon

21
Q

What triggers the depolarization of adjacent axon segments during action potential propagation?

A

an influx of Na+ into the axon triggers this

22
Q

why do action potentials only propagate in one direction?

A

because the regions of the membrane behind the action potential are in their absolute refractory period

23
Q

what are tetrodotoxin (TTX) and lidocain?

A

two nerve agents that disrupt nerve signaling by blocking Na+ channels

24
Q

TTX

A

a sodium channel antagonist; will permanently block Na+ channels preventing them from depolarizing

25
Q

Lidocaine

A

will not permanently block Na+ channels