Lecture54: Proteinurea And Nephrotic Syndrome Flashcards

1
Q

Nephrotic syndrome is characterized by?

A

Proteinurea and Generalized edema

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2
Q

What is the most obvious clinical manifestation of Nephrotic syndrome?

A

Generalized edema

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3
Q

How do we diagnose Nephrotic syndrome?

A

Renal biopsy in tricky cases

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4
Q

What is the most frequent cause of nephrotic syndrome in children?

A

Minimal-change disease

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5
Q

Why is Minimal Change disease given that name?

A

Under LM the glomeruli appear unchanged

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6
Q

What is the Clinical Picture of Minimal change syndrome?

A

Abrupt development of nephrotic syndrome

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7
Q

How do we treat Minimal-change syndrome?

A

Short term corticosteroid therapy

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8
Q

What characterizes Focal Segmental Glomerulosclerosis?

A

Sclerosis of some but not all Glomeruli

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9
Q

How is FSGS differentiated from Minimal change?

A

Presents hypertension and hematuria

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10
Q

Membranous Nephropathy is characterized by?

A

Subepithelial immunoglobulin deposits

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11
Q

Clinical picture of Membranous Nephropathy?

A

Sudden onset of nephrotic syndrome, but doesn’t also respond to corticosteroid therapy

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