Lecture54: Proteinurea And Nephrotic Syndrome Flashcards
Nephrotic syndrome is characterized by?
Proteinurea and Generalized edema
What is the most obvious clinical manifestation of Nephrotic syndrome?
Generalized edema
How do we diagnose Nephrotic syndrome?
Renal biopsy in tricky cases
What is the most frequent cause of nephrotic syndrome in children?
Minimal-change disease
Why is Minimal Change disease given that name?
Under LM the glomeruli appear unchanged
What is the Clinical Picture of Minimal change syndrome?
Abrupt development of nephrotic syndrome
How do we treat Minimal-change syndrome?
Short term corticosteroid therapy
What characterizes Focal Segmental Glomerulosclerosis?
Sclerosis of some but not all Glomeruli
How is FSGS differentiated from Minimal change?
Presents hypertension and hematuria
Membranous Nephropathy is characterized by?
Subepithelial immunoglobulin deposits
Clinical picture of Membranous Nephropathy?
Sudden onset of nephrotic syndrome, but doesn’t also respond to corticosteroid therapy