Lecture48: Induction Of Diuresis

Question 1

Name the two clinical indications of Diuretic prescription?

Answer 1

Combination with anti hypertensives, or to reduce ECF volume

Question 2

Diuretics act on what specifically?

Answer 2

The mechanism for sodium uptake through the apical membrane

Question 3

Osmotic diuretics are administered how?

Answer 3

Via IV infusion.

Question 4

How do Osmotic Diuretics function?

Answer 4

They increase the blood mannitol, and thus it’s filtration

Question 5

Carbonic anhydrases are given in which disease?

Answer 5

Glaucoma

Question 6

Carbonic Anhydrase inhibitors are more so for which time period?

Answer 6

Short term

Question 7

What is the Carbonic Anhydrase inhibitor?

Answer 7

Acetazolamide

Question 8

What is the Loop Diuretic?

Answer 8

Furosemide

Question 9

What do loop diuretics act on?

Answer 9

The thick ascending limb

Question 10

Furosemide, the loop diuretic is given for?

Answer 10

Heart failure or oedemas

Question 11

The Thiazide diuretic acts on what

Answer 11

DCT

Question 12

The Thiazides are given for?

Answer 12

Heart failure and hypertension

Question 13

Why is Thiazide the preferred diuretic for hypertension?

Answer 13

Arterial vasodilation via decreasing sodium load

Question 14

Furosemide causes hypo or hyperkalemia?

Answer 14

Hypokalemia

Question 15

To induce short term osmotic diuresis, we give?

Answer 15

Mannitol via IV

Question 16

Carbonic Anhydrase inhibitors, Acetozolamide have a risk of?

Answer 16

Hypokalemic metabolic acidosis

Question 17

Do Loop Dirutics, Furosemide have the same side effects as Acetozolamide?

Answer 17

Yes

Question 18

Do K sparring diuretics induce hyperkalemia?

Answer 18

Yes

Question 19

What is the K sparring aldosterone antagonist?

Answer 19

Spironolactone