Lecture14: Boobs Flashcards
The covering skin of the boobs are penetrated by?
Lactiferous ducts
Dilated ducts at the bottom of the nipples are called?
Lactiferous sinuses
What is the Areola?
Darkish area around the nipple
What is the Areola rich in?
Receptors for touch and temp that initiate milk secretion during lactation
What happens to the Areola during breast cancer?
Skin changes
The Storms is made up of?
Thick interlobar CT that arise from the Reticular layer of the dermis
The Highly loose cellular CT in the stroma arises from?
The Papillary layer
What are the Suspensory ligaments of cooper?
They suspend the boobs in place to the Pectoral Fascia
The Ducts of the Parenchyma unite to form?
Large Interlobular ducts
What is each Lobe of the Pareynchyma drained by?
A single main Lactiferous duct
What Lactiferous drainage ducts of the Parenchyma are lined by?
Stratified squamous epithelium
What are the alveoli of the Parenchyma arranged in?
Rounded structures
When do Alveoli’s start to form?
At puberty
How does breast cancer spread?
Via Lymphatic drainage
The majority of lymphatic drainage is via vessels that drain Laterally and Superiorly into…?
The Axillary Lymph Nodes
What is the rest of the drainage into..?
The Parasternal Lymph nodes
What is the boob like in childhood?
Little amount of CT stroma, and few ducts lined by flat cells
How do the boobs grow during puberty?
Estrogen. The stroma grows and fat accumulates
Final development of the Duct system requires both…?
Glucocorticoids and Somatotrophins
What stimulates growth of lobules and Alveoli?
Progesterone
In pregnancy, two hormones increase, those are?
Estrogen and Progesterone
What placental hormone is secreted during pregnancy?
HPL
What anterior pituitary hormone is produced during pregnancy?
Prolactin
What does the Alveoli grow during pregnancy?
Milk production
What happens to duct system in pregnancy?
Proliferates, elongates and branches
What does Colostrum do
Growth of gland and engorgement
During Pregnancy, the predominant component is?
Glandular Parenchyma, basically the ducts and alveoli
During lactation, what hormone stimulates milk secretion?
Prolactin
During Lactation, which hormone stimulates milk ejection?
Oxytocin
What type of cells squeeze the milk from the alveoli?
Myoepithelial cells
The lipid content of milk is?
Apocrine
The Protein content in milk is?
Merocrine
What do Myoepithelial cells do?
They contact to squeeze milk out the alveoli
What are the type of cells at empty lumens?
Cuboidal
Which type of cells have milk at their apical parts?
Pyramidal cells