Lecture33: Glycogen Metabolism Flashcards
What is Glycogenesis?
Glycogen synthesis
What is the Glycogenesis regulatory enzyme?
Glycogen synthase
Why doesn’t muscle glycogenolysis contribute to the elevation of blood glucose level?
They don’t have Glucose 6-phosphate
What stimulates glycogen breakdown but inhibits glycogen synthesis aswell?
Glucagon
What promotes a net storage of glucose?
Insulin
What promotes a net glycogen break down?
Epinephrine
Glycogen synthase is activated via?
Dephosporylation
Glycogen Phosphorylase is activated via?
Phosphorylation
What is the most common glycogen storage disease?
Von Gierke/ Type 1 disease
What is Von Gierke disease?
A deficiency in glucose 6-phosphatase
Pancreatic GLUT2 acts as a…?
Glucose sensor
Insulin’s action on carbohydrates is mainly to…?
Decrease blood glucose
Glucagon’s action on carbohydrates is mainly to…?
Increase blood glucose levels