Lecture Test 2 Part Two Flashcards
What is the ABO system?
system of grouping blood according to the presence or absence of antigen A and antigen B
Those who have antigen A on the surface of their RBCs have
type A blood
Those who have antigen B on the surface of their RBCs have
type B blood
Those who have antigen A and antigen B on the surface of their RBCs have
type AB blood
Those with no antigens on the surface of their RBCs have
type O blood
In order to have type O blood:
both parents have to have type O blood
There are ______ in the plasma that will react with the antigens of other blood types.
antibodies
When incompatible bloods are mixed together,
a transfusion reaction occurs
what is a transfusion reaction?
RBCs burst releasing hemoglobin into the blood
what is hemolysis?
bursting of red blood cells
The main reaction to compare when evaluating matches is
donor antigen and recipient antibody
Type A blood has
A antigens
anti B antibodies
Type B blood has
B antigens
anti A antibodies
Type AB blood has
A and B antigens
no antibodies
Type O blood has
no antigens
anti A and anti B antibodies
Who is the universal recipient
AB
Who is the universal donor?
O
Humans are born with
ABO antigens but develop appropriate antibodies
What is the Rh system?
A blood typing first discovered in the rhesus monkey
Those who have Rh antigens on their RBCs
are Rh+
Those who lack Rh antigens on their RBCs
are Rh -
Which typing is most popular on the Rh scale?
Rh+
To be Rh-,
both parents must contribute a Rh gene
Normally there are no ___________ in the blood of Rh - people
anti Rh antibodies
People will develop anti Rh antibodies
after exposure to Rh+ blood
When the mother is Rh - and the fetus is Rh+
hemolytic disease of the newborn may occur
Hemolytic disease of the newborn is only a problem
during a second pregnancy
During labor, the mothers Rh- blood and the baby’s Rh+ blood will mix and
the mother will produce anti Rh antibodies
During the second pregnancy, the mother’s anti Rh antibodies
will cross the placenta.
What is the outcome of hemolytic disease of the newborn?
hypoxia, anemia and brain damage to the fetus
How can hemolytic disease of the newborn be prevented?
rhogam injection during the pregnancy and 72 hours after delivery
What does the Rhogam injection do?
Prevents the mother’s blood from forming the anti Rh antibodies.
When do transfusion reactions occur?
shortly after a mismatched blood transfusion
What does a transfusion reaction cause?
chills, fever, vomiting and possible kidney damage.
Why are the kidneys damaged after a transfusion reaction?
the release of hemoglobin into the blood and blockage of the renal tubules causing renal failure
what is the treatment for a transfusion reaction?
IV fluids, diuretic, antihistamines, steroids
The heart is the ______ of the cardiovascular system
pump
The heart is located
between the lungs in the mediastinum
The heart is enclosed in
a pericardial sac
The pericardial sac has two layers:
fibrous pericardium
serous pericardium
What is the fibrous pericardium?
the outer, tough fibrous connective tissue sac that surrounds the heart.
What is the serous pericardium?
thinner more delicate membrane that is composed of two layers with a small space in between.
The pericardial space is filled with
pericardial fluid
What is pericarditis?
inflammation of the serous pericardium
What are the three portions of the heart wall?
epicardium
myocardium
endocardium
What is the epicardium?
thin membrane that is the external layer of the heart
What is the myocardium?
cardiac muscle layer; involuntary, striated, intercalated discs.
What is the endocardium?
Thin layer of endothelium lining the heart and continues with the endothelium of the vessels.
What is the largest layer of the heart?
myocardium
What is epicarditis?
inflammation of the epicardium
What are the four chambers of the heart?
left atrium
right atrium
left ventricle
right ventricle
What are the superior chambers?
atriums
What are the inferior chambers?
ventricles
The atria are separated by
the interatrial septum
The ventricles are separated by the
interventricular septum
What are the functions of the valves of the heart?
prevent back flow of blood