FINAL!!!!!!!!! Flashcards
What is genetics?
study of the passage of traits from one generation to the next
what are genes?
structure of the DNA which holds the information for genetic traits
Where are chromosomes found?
nuclei of cells
Nuclei of somatic cells contain
46 chromosomes in humans
When is the amount of chromosomes determined?
fertilization
The 46 chromosomes are arranged in
homologous pairs
What are autosomal chromosomes?
chromosomal pairs 1-22
Chromosome pair 23 is
the sex chromosomes
what are sex chromosomes?
chromosomes that determine the sex of the individual
In humans, the mother will donate
the X chromosome
In humans, the father will donate
an X or Y chromosome
What determines the sex of an offspring?
the sperm
XX=
female
XY=
male
Since X and Y are not homologous,
there will be different information on these two chromosomes
The Y chromosome gives the information for
maleness
Male and female embryos develop identically until
7 weeks after fertilization
What happens at 7 weeks of fertilization?
the Y gene will become male. If there is no Y gene a female is the result
what is the SRY gene?
sex determining region of the Y chromosome
How does the SRY function?
it inserts into a genetically female fetus and develops it into a male
When fertilization occurs, the genes inherited from the father
and combined with the genes inherited from the mother
What are alleles?
variations of a gene
An example of an allele is
hair color
Where is the gene for hair color found>
one of the autosomes
If the mother and father contribute the same alleles (both have brown hair)
the person is said to be homozygous
If the alleles are different they are said to be
heterozygous
Dominant alleles control
a particular trait
In order for a recessive trait to be expressed,
the individual needs to have a double dose. I.E. homozygous
what is a genotype?
genetic makeup of an organism
the trait expressed is called the
phenotype
Type A and B blood are
codominant
Type O blood is
recessive
In order for a person to have type O blood,
both parents must be type O
Most genetic disorders are due to
the presence of the recessive gene
In order for a genetic disorder to occur,
the individual must be homozygous recessive
What happens to a heterozygous recessive individual?
they are not affected but can pass the gene off onto their offspring
what are carriers?
heterozygous recessive
what is the most common lethal genetic disease?
cystic fibrosis
what is PKU?
phenylketonuria
what is phenylketonuria?
recessive disease where the individual lacks the enzyme that breaks down phenylalanine (an amino acid)
what does phenylketonuria cause?
brain damage and mental retardation due to the build up of phenylalanine
In most states, there is
mandatory testing of newborns for PKU
In a dominant genetic disorder,
both homozygous and heterozygous are affected
what is huntingtons disease?
degenerative disease of the nervous system
huntingtons disease has no
phenotypic expression until 35-45 years of age
what is a punnett square?
process to determine what % of children will be affected by genetic disorders
What is DNA?
a sequence of nucleotides strung together
DNA is broken down into
chromosomes
chromosomes are broken down into
individual genes
Each gene is coded for
one trait
A human has about how many genes?
35,000
how many genes are on each chromosome?
750
If you are a female you will have
23 paired chromosome
If you are a male, you will have
22 paired chromosomes and one pair that doesn’t match
Y chromosomes have genes for
sex characteristics only
X chromosomes have genes dfor
characteristics and other traits
what is a genotype?
listing of the alleles present
what is a phenotype?
what is visually seen.
What does cystic fibrosis lead to?
increased thickness of mucus
If N is no cystic fibrosis and n is cystic fibrosis:
Nn=carrier
NN=normal
nn=cystic fibrosis
It is important in cell division that
chromosomal pairs divide equally
What is nondisjunction?
unequal distribution of chromosomes in the gametes and problems in the offspring
what is down’s syndrome?
occurs during meiosis and results in an individual with 47 chromosomes instead of 46
What is the extra chromosome in down’s syndrome called?
tripsomy 21 because it is found in the chromosomal pair 21
What does down’s syndrome cause?
mental retardation and some physical problems
what makes down’s syndrome more common?
A mother high in age
What is Turner’s syndrome?
XO. Female because there is no SRY gene. Nonreproductive
what is meta female syndrome?
XXX. True female. Overproduction of estrogen causes health concerns
what is klinefelter’s syndrome?
XXY. Male but will have female characteristics.
klinefelters syndrome will result in
breasts, poor beard growth, wide hips and reduced fertility
what is Jacob’s syndrome?
XYY. nondisjunction. Overproduction of testosterone causes health concerns
What is YO?
will not survive because there is no X chromosome
There are some traits that will be passed on to males but rarely to females, in these cases
the mother is the carrier
what are some problems due to the X chromosome?
color blindness
hemophilia
Only on the X chromosome will there be information for
the development of cones of the eyes
what are the cones of the eyes?
color receptors
the ability to see color is dependant on
the X chromosome
Colorblindness is
recessive
In a female, one X may have the gene for colorblindness but
it will usually be masked by a normal gene on the other X chromosome.
In a male, if the X mom carries the gene for colorblindness,
the Y from dad will not mask it.
What is hemophilia?
a sex-linked condition that results in the inability of the blood to clot
In hemophilia, the X chromosome
contains coding for some essential clotting factors
Hemophilia is rarer in
females
What is hemopoiesis?
the process by which blood cells are formed
what is a hemocytoblasts?
the stem cell that gives rise to RBCs, WBCs and platelets
what is hemoglobin?
4 polypeptide chains with a HEME structure
what is erythropoiesis?
the process of RBC production
what is a reticulocyte?
cell that will mature into a erythrocyte that has a biconcave shape
what is hypoxia?
lack of adequate oxygen in the tissues
what is anemia?
condition of reduced oxygen-carrying ability in the blood
what causes anemia?
reduced levels of hemoglobin
what is polycethemia?
abnormal increase of RBCs that causes the blood to become thicker and less oxygen getting to the tissues
what is a granulocyte?
cells that have 1 lobed nucleus and granules in the cytoplasm
what are some examples of granulocytes?
neutrophils, eosinophils and basophils
what is an agranulocyte?
cells with no granules in the cytoplasm
what are some examples of agranulocytes?
lymphocytes and monocytes
what is chemotaxis?
attraction of phagocytes to microbes by chemical stimulus
what is diapedisis?
process by which WBCs leave the blood
what is a thrombocyte?
platelet
what is a megakaryote?
forms after a hemocytoblasts and will become a thrombocyte
what is hemostasis?
stoppage of bleeding
what is coagulation?
when a clot is formed in the injured area
what is fibrinolysis?
removes the unneeded clot when healing occurs
what is t-pa?
substance that converts plasminogen into plasmin
what is the function of tpa?
removal of the clot
what is plasminogen?
an inactive blood protein
what is a thrombus?
a clot
what is an embolus?
a clot that flows freely in the blood
what is an antigen?
glycolipids on the surface of RBCs that are genetically determined
what are antibodies?
substance found in the plasma that reacts with the antigens of other blood types
what is hemolytic disease of the newborn?
when the mother is RH- and the fetus is Rh +
what are the main components of whole blood?
plasma and formed elements
what are formed elements?
RBC, WBC and platelet
Most of whole blood is
plasma
Most of the formed elements are
RBCs
the absence of a nucleus in a erythrocyte causes
more room for hemoglobin
the biconcave shape of an RBC will result in
increased surface area for gas diffusion and gives the cells flexibility to fit through small vessels/
What is the process of erythropoiesis?
hemocytoblasts
reticulocyte
erythrocyte
hemocytoblasts have
a nucleus
reticulocytes and erythrocytes have
no nuclei
How long does erythropoiesis take?
1-2 days
what is hemorrhagic anemia?
blood loss leading to a decreases number of RBCs
what is hemolytic anemia?
RBCs rupture prematurely
what is aplastic anemia?
pathology of the red bone marrow
what is dietary anemia?
not enough iron in the blood to carry oxygen
what is pernicious anemia?
lack of intrinsic factor
what is sickle cell anemia?
RBC loses its round shape and sickles
what is the function of a neutrophil?
phagocytosis
what is the function of a eosinophil?
parasitic worms
what is the function of a basophil?
heparin and histamines
what is the function of a lymphocyte?
antibody production
what is the function of a monocyte?
phagocytosis
what are the three phases to hemostasis?
vascular spasms
platelet plug formation
coagulation
how long does it take for vascular spasms to occur?
immediately
how long does platelet plug formation take?
1-2 minutes
what are the three phases to platelet plug formation?
platelet adhesion
platelet activation
platelet aggregation
what is the intrinsic pathway of coagulation?
factor 12 calcium factor ten (common pathway) prothrombinase turns prothrombin into thrombin thrombin turns fibrinogen into fibren
what is the extrinsic pathway of coagulation?
factor three calcium factor ten (common pathway) prothrombinase turns prothrombin into throbin thrombin turns fibrinogen into fibren
what is the effect of aspirin on coagulation?
antiprostaglandin prevents prostaglandin from being released. Plug is not formed completely
what is Coumadin?
anticoagulant that inhibits the formation of a clot
what is nitroglycerin?
vasodilator given during a myocardial infarction
Type A blood:
has A antigens and B antibodies
Type B blood has
B antigens and A antibodies
Type AB blood has
A and B antigens and no antibodies
Ty[e O blood has
no antigens and A and B antibodies
who is the universal donor?
type o
who is the universal recipient?
AB
What is the treatment for hemolytic disease of the newborn?
rhogam injections
what is the pericardium?
outer sac that covers the heart
what is the chordae tendinae?
connects the atrioventricular valves to the papillary muscles
what is a myocardial infarction?
heart attack
what is the pacemaker?
the SA node that sets up the impulse.
what is a heart murmur?
sound heard before the lubb-dupp that masks the normal heart sounds
what causes a heart murmur?
a valve not closing completely
what is systole?
phase of contraction
what is diastole?
phase of relaxation
what is cardiac output?
amount of blood ejected by the left ventricle per minute
what is stroke volume?
amount of blood ejected from the left ventiricle per beat
what is starlings law?
an increased preload due to exercise leads to an increase in cardiac output by causing an increase in stroke volume
what are beta blockers?
medication given to decrease the heart rate
what composes the pericardial sac?
fibrous pericardium
serous pericardium
what is the fibrous pericardium?
outer layer that surrounds the heart
what is the serous pericardium
thinner membrane with 2 layers
what are the two layers of the pericardium?
parietal and visceral pleura with a pericardial space
what is the epicardium?
external layer of the heart
what is the myocardium?
cardiac muscle layer of the heart. largest layer
what is the endocardium?
thin layer of endothelium lining the heart continuous with the endothelial lining of the vessels
what are the four chambers of the heart?
right and left atrium
right and left ventricles
what are the four valves of the heart?
aortic semilunar valve
pulmonary semilunar vavle
tricuspid
bicuspid
where does the impulse start in the heart
SA node
what is the p wave of an EKG represent?
spread of impulse from the SA node throughout the atria leading to contraction of the atria
what does the t wave represent?
ventricular repolarization
what is the PQ interval?
beginning of atrial excitation to the beginning of ventricular excitation
what is the QT interval?
start of the QRS complex to the end of the T wave
when are the cuspid valves open?
atrial systole
when are the cuspid valves closed?
ventricular systole
When are the semilunar valves open?
ventricular systole
How do you change the cardiac output?
change the stroke volume or heart rate
How does the sympathetic nervous system affect the cardiac output?
releases noephrinepine which increases the heart rate.
How does the parasympathetic nervous system affect the nervous system?
releases acetycholine which slows down the heart rate
what is an artery?
carries blood away from the heart (usually oxygenated)
what is an arteriole?
connects arteries with capillaries
what is a capillary?
site of material moving in and out of the circulatory system
what is a venule?
connects capillaries with the veins
what is a vein?
carries blood towards the heart
what is bulk flow?
large amounts of ions, proteins, other nutrients and water
what is an edema?
abnormal increase in interstitial fluid
What is hypotension?
low blood pressure
what is hypertension?
high blood pressure
what is an aneurysm?
localized dilation of an artery normally found in the brain or aorta
what is altherosclerosis?
fatty deposits forming in the vessel wall and sometimes bulging into the lumen
what is the result of altheroscelerosis?
blood clots
what is arteriosclerosis?
end product of altherosclerosis. vessels lose their elasticity
what is shock?
inadequate perfusion of tissues
what are the layers of arteries and veins?
tunica interna
tunica media
tunica externa
what is the thickest layer of the arteries?
tunica media
what layer is the thickest in veins?
tunica externa
Explain bulk flow
hydrostatic pressure pushes nutrients into the arteriole side. Oncotic pressure pushes wastes into the venule side
what are the causes of edema?
heart problems
fluid retention
increased capillary permeability
How does bulk flow cause edema?
when filtration and reabsorption of interstitial fluid is interrupted
where can a pulse be detected on the wrist?>
radial artery
where can a pulse be detected on the neck?
carotid artery
where can a pulse be detected in the groin?
femoral artery
where can a pulse be detected in the foot?
dorsal pedal artery
where can you detect a pulse on the elbow?
brachial artery
what are the three branches that come off the aortic arch?
brachiocephalic
left common carotid
left subclavian
where are blood samples taken from?
median cubital vein
how does fetal circulation differ from adult?
there are no lungs and the fetus obtains its oxygen from diffusion
At birth, what happens to the ductus venosus?
becomes ligamentum venosum
At birth, what happens to the ductus arteriosus?
becomes ligamentum arteriosum
At birth, what happens to the foramen ovale?
becomes fossa ovalis
at birth, what happens to the umbilical vein?
becomes round ligament
what happens to the umbilical arteries at birth?
becomes cords of umbilical arteries
what is hemhorragic shock?
hypovolemia. external or internal bleeding
what is plasma loss shock?
hypovolemia. loss of plasma to the interstitial spaces
what is dehydration shock?
hypovolemia due to extreme urination
what is anesthesia shock?
vasodilation. decreased activity of the medulla
what is anaphylactic shock?
vasodilation. allergic reaction
what is septic shock?
vasodilation. infection of the blood
what is neurogenic shock?
vasodilation. head injuries
what is the thoracic duct?
drains lymph from everywhere except the right arm, neck and head
what is lymph?
interstitial fluid and proteins in the lymphactic capillaries
what is the lymph node?
germination centers that filter lymph
what is the thymus?
secretes hormones and matures t cells
what is the spleen?
removes old rbcs and serves as a blood reservoir
tonsils:
MALT
MALT:
mucosa associated lymphatic tissue
what is hodkins disease?
cancer of the lymph nodes
what is innate immunity?
nonspecific defense
what is adaptive immunity?
specific immunity
what is interferon?
substance produced by cells that is toxic to viruses
what is complement?
major mechanism for destroying foreign substances in the body
what is opsonization?
improving or enhancing phagocytes
what are pyrogens?
pyrogens stimulate prostaglandins which increase the thermostat resulting in a fever
what is an epitope?
specific regions of antigens recognized by specific b and t cells
what are major histocompatibility complexes?
lymphocyte recognition that starts cell division
what are antigen presenting cells?
macrophages that disply a portion of the antigen on its surface
what is interleukin 2?
cytokine needed for all adaptive immunity responses
what is an autoimmune disease?
immune system fails to recognize self and launches an attack against its own tissues
what is an allergy?
over reaction to an antigen that is tolerated by most others
what is anaphylaxis?
severe reaction resulting in mass vasodilation
what is an opportunistic infection?
AIDS HIV
what are the three components of the lymphatic system?
cells
lymphatic vessels
lymphoid tissues and organs
what are lymphatic cells?>
lymphocytes
monocytes
neutrophils
what is the route of lymph?
lymphatic capillaries afferent lymphatic vessels lymph nodes efferent lymphatic vessels lymphatic trunks lymphatic ducts
where does lymph rejoin the blood?
lymphatic ducts
what is the function of the spleen?
remove old and dying RBCs
how does innate immunity differ from adaptive immunity?
innate immunity protects the body from all invaders where the adaptive is specific
what does interferon protect?
neighboring cells
what does membrane attack complex do?
punches holes in cell walls
what is the function of natural killer cells?
to police the body for invaders
what do natural killer cells secrete?
perforins
How do natural killer cells function?
they attach themselves to the invader and destroy their membranes
what are the four signs of inflammation?
heat
redness
swelling
pain
how does inflammation protect the body?
prevents the spread
disposes debris and pathogens
sets stage for repair
why is there redness and heat?
dilation of blood vessels
what causes the swelling?
more fluid escaping the vessels
what causes the pain?
edema putting pressure on nerves
what are helper t cells?
produce cytokines specifically interleukin 2
what are cytotoxic t cells?
directly destroy the invader
memory t cells:
programmed to destroy the same invader at a different date
B cells differentiate into
memory cells or plasma cells
what are the different types of antibodies?
IgG IgA IgM IgD IgE
IgG:
most abundant
IgE:
involved with allergic reactions
what is the secondary response?
the later exposure causes memory cells to quickly respond to the invader
what is lag time?
time between invasion of antigen into body and the appearance of antibodies
what are the four types of immunity?
active natural
passive natural
active artificial
passive artificial
what is the cause of AIDS?
HIV
HIV is caused by
bodily secretions
what cells are affected by HIV/AIDS?
helper t cells
macrophages
brain cells
what enzyme is needed for HIV?
reverse transcriptase
what is the treatment for HIV/AIDS?
AZT and protease inhibitors
what is AZT?
reverse transcriptase inhibitor
what is the larynx?
voicebox connecting the vocal cods
what is the epiglottis?
keeps you from choking by closing the larynx
what are vocal cords?
true–voice
false–protection
what are bronchi?
trachea primary bronchi secondary bronchi tertiary bronchi bronchioles terminal bronchioles
parietal pleura?
outer layer attached to the wall of the thoracic cavity
what is the visceral pleura?
inner layer covering the lungs
what is an asthma attack?
smooth muscle contractions that decrease the diameter of the airway
type I pneumocytes:
cells where actual gas exchange occurs
surfactant:
prohibits internal lung surfaces from sticking together
pulmonary ventilation
breathing
inspiration:
inhalation
expiration:
exhalation
Boyle’s Law
pressure of a gas in a closed container is proportionate to the volume of the container
external respiration:
exchange of oxygen and carbon dioxide between the air and the alveoli and blood in the capillaries
Dalton’s law:
each gas in a mixture exerts its own pressure as if the other gases were not present
internal respiration:
exchange of oxygen and carbon dioxide between the blood and the cells
what is partial pressure?
the pressure of a specific gas in a mixture noted by pO2 and pCO2
tidal volume:
one breath in and out
Most of the carbon monoxide from the cells are transferred as
bicarbonate ions
apnea
absence of breathing
emphysema:
alveolar walls disintegrate producing large sacs in which air remains even after exhaling
what is the upper respiratory tract?
above the larynx
what is the lower respiratory tract?
below the larynx
what is the conducting airway?
primary bronchi to terminal bronchi
what is the respiratory airway?
respiratory bronchioles to the alveoli
what is the function of septal cells?
produce surfactant
what is the function of type I pneumocytes?
where actual gas exchange occurs
what are the gonads?
reproductive organs
what are gametes?
testes and ovaries
what is an oocyte?
eggs
what is a diploid?
46 chromosomes
haploid:
23 chromosomes
cremaster muscle:
muscle that regulates temperature of the testes
cryptorchidism:
testes do not descend
seminiferous tubule:
where sperm develop and mature
what is hyperthermia?
heat gain exceeds heat loss
what is hypothermia?
heat loss exceeds heat gains
what is metabolism?
chemical reactions that gain heat
what is basal metabolism?
energy that keeps resting body functioning
what is radiation?
UV light (gain)
what is conduction?
transfer of heat between objects that are in contact (gain and loss)
what is convection?
heats the air (gain and loss)
what is evaporation?
sweat (loss)
Most of your energy is used for
basal metabolic rate
the least amount of energy is used for
thermic effect of food
what is thermic effect of food?
energy needed for digestion
what is muscle activity
energy used for movement
anaerobic respiration:
no oxygen
no mitichondia
glycolysis followed by fermentation
2 ATP
aerobic respiration
oxygen
mitochondria
glycolysis, Krebs, etc
38 ATP
what is digestion?
breakdown of food molecules into smaller molecules
what is an enzyme?
increases the rate of chemical reactions
mastication:
chewing
deglutition:
swallowing
peristalsis:
involuntary muscle contractions
sphincter:
muscle that constricts an opening
diabetes mellitus:
inability to produce insulin. blood glucose levels rise and none reach the cells
hepatic portal vein
takes carbs to the liver and then the rest of the body
what are the layers of the digestive tract?
tunica mucosa
tunica submucosa
tunica muscularis
tunica serosa
what composes the tunica mucosa?
epithelium
lamina propria
muscularis mucosa
what is the total transit time of the GI tract?
24-36 hours
what is the length of the GI tract?
25-28 feet
what is the longest organ of the GI tract?>
small intestine 21 feet
what is the longest transit time of the GI tract?
large intestine 18-24 hours
what is digested in the mouth?
carbs by salivary amylase
what is digested in the stomach?
proteins
what is digested in the small intestine?
disaccharides and peptidases
what is digested in the large intestine?
proteins and some carbs
what enzyme is secreted in the mouth?
salivary amylase
what enzyme is secreted in the small intestine?
disaccharidases
what does the pancreas secrete?
pancreatic amylase
what does the large intestine secrete?
e coli
what are the functions of the liver?
carb metabolism lipid metabolism protein metabolism production of bile detoxification storage protection synthesis
what is type 1 diabetes?
juvenile onset, insulin dependent
what are the symptoms of diabetes?
polyuria
polyphagia
polydipsia
what is type 2 diabetes?
adult onset, obesity, noninsuling dependant
what cells produce insulin?
beta cells
bile is stored in the
gallbladder
bile is produced in the
liver
who makes bile?
hepatocytes
cortex
the outside region of the kidney
medulla:
outer layer of the kidney
nephron:
functional unit of the kidney
what is the renal tubule
PCT
DCT
Loop of Henle
Collecting Duct
glomerulus
tuft of capillaries closely associated with bowmans capsule
what is ADH?
antidiuretic hormone
what is the function of ADH
decreasing urine output by increasing the permeability of the DCT and CD
what stimulates the secretion of ADH?
hypotension
What is the stimulus to release aldosterone?
low blood volume
what is the result of aldosterone being released?
increase in blood volume
what is diabetes insipidus?
hyposecretion of ADH
What is the result of diabetes insipidus?
massive amount of urination leading to dehydration
what is the treatment for diabetes insipidis?
exogenous ADH
what is dialysis?
separation of large solutes through a selectively permeable membrane
what are the two types of dialysis?
hemodialysis
continuous ambulatory peritoneal dialysis CAPD
function of the urinary system
controlling blood volume, pH and concentration RBC production forming and eliminating urine regulating blood pressure vitamin D synthesis
what decides the formation of filtrate?
filtration pressure
what is the major site of tubular reabsorption
PCT
where is the site forsecretion
PCT DCT
what is the effect of ADH?
increases permeability of water
what is the pathway for aldosterone secretion?
renin released
angiotensinogen into angiotensin 1
angiotensin converting enzyme turns angiotensin 1 into angiotensin 2 which increases aldosterone secretion
what is the pathway through the urinary system?
glomerulus bowmans cpsule pct loh dct cd
seminal vesicles
paired glands that secrete alkaline
prostate gland:
gland that secretes substance that coagulates semen
bulbourethral gland
secretes alkaline mucus substance that lubricates the penis and prepares for ejaculation of sperm
the penis contains
2 corpora cavernosa and a corpus sponginosum
GnRH
gonadotropin releasing hormone
function of GnRH
stimulate the anterior pituitary gland
FSH
follicle stimulating hornone
function of FSH
stimulates spermatogenesis
LH
leutinizing hormone
function of LH?
carried to interstitial endocrinocytes and stimulates testosterone secretion
primordial follicles
females are born with these follicles that mature into primary follicles
primary follicles undergo
atresia
atresia:
degeneration
some primary follicles become
secondary follicles
secondary follicles
one of these follicles will develop into a graafian follicle
graafian follicle
ruptures releasing the secondary oocyte
ovulation
final maturation of the secondary follicle in the fallopian tube
corpus luteum
ruptured follicle that remains in the ovary
corpus luteum secretes
estrogen and progesterone
corpus albicans
corpus luteum becomes scar tissue called albicans
endometrium
innermost layer of the uterus
what are the two layers of the endometrium
stratum functionalis
stratum basalis
cervix
distal portion of the uterus
clitoris
homologous to the male penis
menstruation in the uterus
stratum functionalis detaches producing flow
menstruation in the ovaries
primordial follicles into primary follicles
capacitation
membrane of sperm and acrosome become fragile
acrosomal reaction
sperm releases hyaluronidase causing disruption of the corona radiata and zona pellucida
fertilization:
genetic material of sperm and oocyte merge to form a single nucleus
implantation
blastocyst attaches to endometrium and secretes enzymes that penetrates the stratum functionalis
zygote
46 chromosomes
morula
solid ball of blastomeres surrounded by the zona pellucida
blastocyst
when a cavity forms in the middle of the morula
monozygotic twins
one oocyte and one sperm but two areas of the cell develop
dizygotic twins
mother ovulates two oocytes and both are fertilized
embryoblast
becomes baby
trophoblast becomes
placenta
endoderm
inner layer, most viscera
ectoderm
outside layer, skin and nervous system
mesoderm
middle layer. muscle, bone and connective tissue
yolk sac
early site of blood formation
amnion
membrane filled with amniotic fluid
chorion
membrane that becomes part of the placenta
placenta
responsible for bringing O2 to the baby and taking away CO2
gestation
time a zygote, embryo or fetus is carried
parturition
delivery
How is temperature maintained in the testes?
cremaster muscle pulls the testes up when cold and pulls them down when hot
Why is temperature regulation important to the testes
survival of sperm needs a temperature lower than core body temp
what are the cells responsible for spermatogenesis?
spermatogonial cells
what cells are responsible for testosterone secretion?
interstitial endocrinocytes
what are the parts of the spermatozoa?
head
midpiece
flagella
what is found in the head of a spermatozoa?
genetic material and the acrosome that contains enzymes
what does the midpiece of the spermatozoa contain?
mitochondria
How many chromosomes does a spermatozoa contain?
23
Pathway for spermatozoa:
seminiferous tubules epididymis vas deferens ejaculatory ducts prostatic urethra membranous urethra spongy urethra
what are the male accessory glands?
seminal vesicles
prostate gland
bulbourethral gland
what do seminal vesicles secrete?
alkaline
what do prostate glands secrete
milky-white, slightly alkaline substance that coagulates semen
what do bulbourethral glands secrete?
alkaline mucus substance that lubricates the tip of the penis and prepares for ejaculation
how is an erection accomplished?
pudendal nerve
nitrous oxide mixes with guanylate cyclase
GC converts GTP to cGMP
cGMP causes dilation
what days are menstruation?
1-5
what days are preovulation
6-13
what day is ovulation?
14
what days are postovulatory?
15-28
what happens to the uterus during menstruation
stratum functionalis detaches
what happens to the uterus during preovulatory phase?
beginning of new stratum functionalis due to estrogen
what happens to the uterus during ovulation
s functionalis thickens
what happens to the uterus during post ovulatory phase
s functionalis continues to develop due to high progesterone
what happens to the ovaries during menstruation?
primordial into primary and secondary
what happens to the ovaries during preovulatory phase?
secondary into graafian
what happens to the ovaries during ovulation?
oocyte expelled into fallopian
what happens to the ovaries during postovulatory phase?
corpus luteum present
what are hormone levels during menstruation?
FSH–LOW
LH–LOW
EST–LOW
PROG–LOW
WHAT ARE HORMONE LEVELS DURING PREOVULATROY PHASE
FSH–INCREASING
LH–LOW
EST–INCREASING
PROG–LOW
WHAT ARE HORMONE LEVELS DURING OVULATION
FSH–PEAKS
LH–PEAKS
EST–PEAKS
PROG–LOW
WHAT ARE HORMONE LEVELS DURING POSTOVULATORY PHASE
FSH–LOW
LH–LOW
EST–DECREASING
PROG–INCREASING
what type of method is abstinence?
behavioral
what type of method is borth control pills?
hormonal. prevents ovulation
what type of method is implant
behavioral–prevents fertilization
what type of method is IUD
mechanical–prevents fertilization
what type of method is diaphragm?
mechanical–prevents fertilization
what type of method is spermicide
mechanical–prevents fertilization
what type of method is rhythm
behavioral–prevents fertilization
what type of method is temperature
behavioral–prevents fertilization
what type of method is mucus?
behavioral–prevents fertilization
what type of method is depoprovera
hormonal–prevents ovulation
what type of method is nuvo-ring?
hormonal–prevents ovulation
what type of method is tubal ligation
behavioral–prevents fertilization
what type of method is condom
mechanical–prevents fertilization
what type of method is coitus interruptus
behavioral–prevents fertilization
what type of method is vasectomy?
mechanical–prevents fertilization
where does fertilization occur?
fallopian tube
when does fertilization occur?
12-24 hours after ovulation
where does implantation occur?
uterus
when does implantation occur?
6-7 days after fertilization
what is the pathway for fetal production
pronuclei zygote 2 cell morula blastocyst
what stage of fetal production enters the uterus
blastocyst on day 20
what layer does the yolk sac come from?
endoderm
what germ layer does the amnion come from
ectoderm
what germ layer does the chorion come from
endoderm
what germ layer does the atlantis come from
endoderm
hCG
human chorionic gonadotropin
what is the function for human chorionic gonadotropin
stimulus for more progesterone by corpus luteum
why is hCG important
becomes measurable on pregnancy test on day 22
how long is gestation
266 days from ovulation
how long is gestation if ovulation is not known?
280 days from last period
what are the three stages of parturition
stage of dilation
stage of expulsion
placental stage
what happens during the stae of dilation
uterine contractions
rupture of the amniotic sac
what happens during the stage expulsion
baby is dellivered
what happens at the placental stage
placenta is passed
how long is the stage of dilation
hours
how long is the stage of expulsion
minutes
how long is the placental stage
minutes
what hormone begins parturition
ACTH
who is responsible for parturition
baby