Lecture Exam 3 - Chapter 9 Flashcards
_________ muscle – muscles attached to bone
Skeletal
_________ muscle:
Function – produce movement by pulling on bone
Skeletal
_________ muscle – muscle of the heart
Cardiac
_________ muscle:
Function – pushes blood through the circulatory system
Cardiac
_________ muscle – lines the hollow organs
Smooth
_________ muscle:
Function – pushes things through and out of the body
Smooth
- Properties of muscle -
_________ – ability to respond to nerve impulses
Electrical excitability
- Properties of muscle -
_________ – ability to contract and generate force
Contractility
- Properties of muscle -
_________ – ability to stretch without being damaged
Extensibility
- Properties of muscle -
_________ – ability to return to its original shape and size
Elasticity
-four functions of skeletal muscle-
_________ – muscle contracts pulling on the tendon which moves a bone (i.e. running, walking, nodding the head)
Produce movement
-four functions of skeletal muscle-
Produce movement:
- _________ muscle moves blood throughout the body
- _________ muscle moves substances (food, urine, etc.) through and out of the body
- Cardiac
- Smooth
-four functions of skeletal muscle-
_________ – some muscles are always active to allow us to sit up, stand, etc.
Maintain posture and body position
-four functions of skeletal muscle-
Muscles _________ joints and help keep them _________
- cross
- stable
-four functions of skeletal muscle-
_________ – when a muscle contracts, heat is given off as a waste product
Maintenance of body temperature
- Three layers of connective tissue -
_________ – surrounds the whole muscle
–Separates the muscle from surrounding structures
Epimysium
- Three layers of connective tissue -
_________ – divides muscle into bundles of muscle cells called fascicles
–Also contains blood vessels and nerves that supply the muscle
Perimysium
- Three layers of connective tissue -
_________ – surrounds individual muscle cells
–Contains capillaries, cells to repair muscle, and nerves that control the muscle
Endomysium
Muscle requires a large amount of blood supply to bring in _________ and nutrients and carry away _________ products
- oxygen
- waste
Muscle cell = muscle _________
fiber
“_________” means muscle
Sarco
_________ – cell membrane of a muscle cell
Sarcolemma
_________ – cytoplasm of a muscle cell
Sarcoplasm
_________ – extensions of the sarcolemma
T tubules
_________ – organelle that stores calcium
Sarcoplasmic reticulum
-Sarcoplasmic reticulum-
- Tubular network surrounds each _________
- Terminal _________ – enlarged areas of the sarcoplasmic reticulum
- _________ is released from the TC
- Release of calcium from the terminal cisternae is the first step in muscle _________
- myofibril
- cisternae
- Calcium
- contraction
- Sarcomere -
_________ mark the border of a sarcomere
Z lines or Z discs
- Sarcomere -
_________ is the center of the thick filament
M line
- Sarcomere -
_________ are the dark bands
A bands
- Sarcomere -
_________ are the light bands
I bands
- Sarcomere -
_________ light area on either side of the M line
H zone
- Sarcomere -
_________ – overlap of thin and thick filaments
Zone of Overlap
_________ filaments – made up of myosin
Thick
_________ filaments – made up of actin
Thin
- Muscle Proteins -
_________ – motor protein found in thick filaments
Myosin
- Muscle Proteins -
_________ - interacts with actin
Myosin
- Muscle Proteins -
_________ – thin filaments made up of a twisted strand of actin molecules
Actin
- Muscle Proteins -
Each actin molecules has an “active” site where it will bind with _________ during muscle contraction
-myosin
- Muscle Proteins -
_________ – double stranded protein that covers active sites on the actin molecules
Tropomyosin
- Muscle Proteins -
_________ – protein that sits on top of the tropomyosin
Troponin
- Muscle Proteins -
_________ –
Attached to the Z disc at each end of the sarcomere
Troponin
- Muscle Proteins -
_________ – large protein that anchors thick filament to a Z disc and the M line
Titin
_________ filaments connect to the thin and pull them to the center of the _________ .
- Thick
- sarcomere
_________ – pressure applied TO something – pulling on a rope, carrying a book
Tension
_________ – force that opposes movement
Resistance
Tension must overcome _________ in order for movement to occur
resistance
Connection between a motor neuron and a muscle fiber is called the _________
neuromuscular junction
- four steps in the neuronal stimulation of a muscle -
- Release of _________ into the _________ cleft (space)
- ACh binds to the _________ on the muscle
- Action potential continues on the muscle in the sarcolemma and is carried to all parts of the fiber by the T tubules
- Return to rest – ACh is broken down by ACHe and action potential is over
- ACh
- synaptic
- receptors
- four steps in the neuronal stimulation of a muscle -
- Release of ACh into the synaptic cleft (space)
- ACh binds to the receptors on the muscle
- _________ potential continues on the muscle in the _________ and is carried to all parts of the fiber by the _________
- Return to rest – ACh is broken down by ACHe and action potential is over
- Action
- sarcolemma
- T tubules
- four steps in the neuronal stimulation of a muscle -
- Release of ACh into the synaptic cleft (space)
- ACh binds to the receptors on the muscle
- Action potential continues on the muscle in the sarcolemma and is carried to all parts of the fiber by the T tubules
- Return to _________ – ACh is broken down by _________ and action potential is over
- rest
- ACHe
-Excitation-Contraction Coupling-
- Action potential travels along the _________
1. Causes the release of _________ into the sarcoplasm from the terminal cisternae of the sarcoplasmic _________
2. Binds to troponin, which causes tropomyosin to move in between the strands of actin - -This exposes the binding sites on the actin
- sarcolemma
- calcium
- reticulum
-Excitation-Contraction Coupling-
- Action potential travels along the sarcolemma
1. Causes the release of calcium into the sarcoplasm from the terminal cisternae of the sarcoplasmic reticulum
2. Binds to _________, which causes _________ to move in between the strands of actin - -This exposes the binding sites on the actin
- troponin
- tropomyosin
-Excitation-Contraction Coupling-
- Action potential travels along the sarcolemma
1. Causes the release of calcium into the sarcoplasm from the terminal cisternae of the sarcoplasmic reticulum
2. Binds to troponin, which causes tropomyosin to move in between the strands of _________ - -This exposes the _________ sites on the actin
- actin
- binding
- Contraction Cycle -
- ATP splits – into ____ (adenosine diphosphate) and a _________ group
- Head of the myosin attaches to the binding site (cross bridge)
- Cross bridge flexes (myosin head bends), moving the thin filament toward the middle of the sarcomere
- -Called the “power stroke” - ATP binds with the myosin head, which releases the myosin head from the actin
- ADP
- phosphate
- Contraction Cycle -
- ATP splits – into ADP (adenosine diphosphate) and a phosphate group
- Head of the _________ attaches to the _________ site (cross bridge)
- Cross bridge flexes (myosin head bends), moving the thin filament toward the middle of the sarcomere
- -Called the “power stroke” - ATP binds with the myosin head, which releases the myosin head from the actin
- myosin
- binding
- Contraction Cycle -
- ATP splits – into ADP (adenosine diphosphate) and a phosphate group
- Head of the myosin attaches to the binding site (cross bridge)
- Cross bridge _________ (myosin head bends), moving the _________ filament toward the middle of the _________
- -Called the “power stroke” - ATP binds with the myosin head, which releases the myosin head from the actin
- flexes
- thin
- sarcomere
- Contraction Cycle -
- ATP splits – into ADP (adenosine diphosphate) and a phosphate group
- Head of the myosin attaches to the binding site (cross bridge)
- Cross bridge flexes (myosin head bends), moving the thin filament toward the middle of the sarcomere
- -Called the “power stroke” - ATP binds with the _________ head, which releases the myosin head from the _________
- myosin
- actin
- Relaxation -
- When _________ impulse stops, release of ____ stops
- Calcium is returned to the terminal cisternae – requires energy (ATP)
- When calcium is take back by the SR, troponin changes shape and tropomyosin once again covers the binding sites on the actin
- -Muscle relaxes
- nerve
- ACh
- Relaxation -
- When nerve impulse stops, release of ACh stops
- _________ is returned to the terminal _________ – requires energy (ATP)
- When calcium is take back by the SR, troponin changes shape and tropomyosin once again covers the binding sites on the actin
- -Muscle relaxes
- Calcium
- cisternae
- Relaxation -
- When nerve impulse stops, release of ACh stops
- Calcium is returned to the terminal cisternae – requires energy (ATP)
- When calcium is take back by the ___, troponin changes shape and _________ once again covers the binding sites on the actin
- -Muscle relaxes
- SR
- tropomyosin
One motor neuron and all the fibers it supplies is a _________
motor unit
_________ number of fibers per neuron – fine motor skills; precise control (fingers, eyes)
-Low
_________ number of fibers per neuron – less precise movement (large thigh and leg muscles)
-High
- Three phases of muscle twitch -
_________ – time it takes for the action potential to travel across the sarcolemma and calcium to be released from the SR
Latent period
- Three phases of muscle twitch -
_________ – peak of tension
–Calcium binds to troponin, active sites are exposed, cross bridges are formed
Contraction phase
- Three phases of muscle twitch -
_________ – muscle returns to rest
–Calcium levels fall, active sites are covered, and cross bridges detach
Relaxation
- Muscle is stimulated a second time before relaxation phase has ended
- Second contraction is significantly stronger than the first: Called _________
wave summation
_________ – muscle is never allowed to relax completely
Incomplete (unfused) tetanus
_________ – relaxation phase doesn’t occur at all
Complete (fused) tetanus
_________ – as strength of the stimulus increases, more muscle fibers contract
Multiple motor unit summation
Multiple motor unit summation:
- Some motor units respond to weak stimulus, some require a stronger stimulus
- More and more motor units are activated as the signal strength increases – called _________
recruitment
_________ contraction – muscle length changes (includes walking running, lifting)
Isotonic
_________ contraction – muscle length doesn’t change, and tension doesn’t exceed resistance
(Holding a baby, standing up, carrying a book)
Isometric
_________ metabolism – uses oxygen to produce ATP
Aerobic
_________ metabolism – does not require oxygen
Anaerobic
Three types of _________ :
- fast
- slow
- intermediate
Muscle Fibers
-Three types of Muscle Fibers-
_________ – most common type; large in diameter
- Produce fast, powerful contractions, but fatigue rapidly
- Used in sprinting and weight lifting
Fast glycolytic fibers
-Three types of Muscle Fibers-
Fast glycolytic fibers-
- Produce fast, powerful _________, but _________ rapidly
- Used in sprinting and weight lifting
- contractions
- fatigue
-Three types of Muscle Fibers-
_________ – smaller fibers
- Take longer to contract, but can contract for longer periods of time
- Have a more abundant blood supply
- Used in running long distances, walking, maintaining posture
Slow oxidative fibers
-Three types of Muscle Fibers-
Slow oxidative fibers – smaller fibers
- Take _________ to contract, but can contract for longer periods of time
- Have a more abundant _________
- Used in _________ long distances, walking, maintaining posture
- longer
- blood supply
- running
-Three types of Muscle Fibers-
_________ – in between slow and fast in both size and endurance
Fast oxidative fibers (intermediate)
-Differences in Cardiac Muscle-
- _________ are smaller and usually only have one _________
- No terminal cisternae – sarcoplasmic reticulum is connected directly to the sarcolemma and T tubules
- Uses aerobic metabolism almost exclusively
- Intercalated discs – specialized cell junctions
- Cells
- nucleus
-Differences in Cardiac Muscle-
- Cells are smaller and usually only have one nucleus
- No _________ cisternae – sarcoplasmic reticulum is connected directly to the _________ and T tubules
- Uses aerobic metabolism almost exclusively
- Intercalated discs – specialized cell junctions
- terminal
- sarcolemma
-Differences in Cardiac Muscle-
- Cells are smaller and usually only have one nucleus
- No terminal cisternae – sarcoplasmic reticulum is connected directly to the sarcolemma and T tubules
- Uses _________ metabolism almost exclusively
- _________ discs – specialized cell junctions
- aerobic
- Intercalated