Lecture Exam 1 - Chapter 5 Flashcards
__________ – superficial epithelium
Epidermis
__________ – underneath, made up of connective tissue
Dermis
6 Functions of skin and hypodermis:
- Regulates __________
- Stores blood
- Protects body from the __________
- Detects cutaneous sensations
- Excretes and absorbs substances
- Synthesizes vitamin D
- body temperature
- external environment
6 Functions of skin and hypodermis:
- Regulates body temperature
- Stores
- Protects body from the external environment
- Detects cutaneous sensations
- __________ and __________ substances
- Synthesizes vitamin D
- blood
- Excretes
- absorbs
6 Functions of skin and hypodermis:
- Regulates body temperature
- Stores blood
- Protects body from the external environment
- Detects __________ sensations
- Excretes and absorbs substances
- Synthesizes __________
- cutaneous
- vitamin D
__________ skin – covers most of the body
- Four layers of keratinocytes
- About as thick as a plastic sandwich bag
Thin
Thin skin – covers most of the body
- Four layers of __________
- About as thick as a __________
- keratinocytes
- plastic sandwich bag
__________ skin – palms of the hands and soles of the feet
-As thick as a paper towel
Thick
Thick skin – palms of the hands and soles of the feet
-As thick as a __________
-paper towel
Cells of the Epidermis:
-
- Melanocytes
- Merkel cells
- Keratinocytes
- Langerhans cells
Cells of the Epidermis:
-Langerhans cells
-
- Melanocytes
- Merkel cells
-Cells of the Epidermis-
__________ – epithelial cells of epidermis
- Several layers of cells
- Produce keratin
Keratinocytes
-Cells of the Epidermis-
Keratinocytes – epithelial cells of epidermis
- __________ layers of cells
- Produce __________
- Several
- keratin
-Cells of the Epidermis-
__________ – found in the deepest layer, produce brown/black pigment melanin
- Contributes to skin color and absorbs UV light
- Projections transfer melanin to keratinocytes
Melanocytes
-Cells of the Epidermis-
Melanocytes – found in the deepest layer, produce brown/black pigment __________
- Contributes to skin color and absorbs __________
- Projections transfer melanin to __________
- melanin
- UV light
- keratinocytes
-Cells of the Epidermis-
__________ – part of the immune system that responds to invaders that make it through the outer layer of skin
Langerhans cells
-Cells of the Epidermis-
Langerhans cells – part of the immune system that responds to __________ that make it through the outer layer of __________
- invaders
- skin
-Cells of the Epidermis-
__________ – connected to a sensory neuron called a Merkel disc
-Function together in the sensation of touch
Merkel cells
-Cells of the Epidermis-
Merkel cells – connected to a sensory neuron called a Merkel disc
-Function together in the __________ of touch
sensation
5 Layers of the Epidermis are:
- Stratum __________
- Stratum Spinosum
- Stratum Granulosum
- Stratum __________
- Stratum Corneum
- basale
- Lucidum
5 Layers of the Epidermis are:
- Stratum basale
- Stratum __________
- Stratum Granulosum
- Stratum Lucidum
- Stratum __________
- Spinosum
- Corneum
5 Layers of the Epidermis are:
- Stratum basale
- Stratum Spinosum
- Stratum __________
- Stratum Lucidum
- Stratum Corneum
Granulosum
-5 Layers of the Epidermis-
Stratum __________ – deepest layer
- Main cells are basal cells – single row of stem cells that reproduce to replace keratinocytes that are shed
- Merkel cells – sensitive to touch
- Melanocytes – give skin its color
basale
-5 Layers of the Epidermis-
Stratum basale – deepest layer
- Main cells are basal cells – single row of __________ cells that reproduce to replace __________ that are shed
- Merkel cells – sensitive to touch
- Melanocytes – give skin its color
- stem
- keratinocytes
-5 Layers of the Epidermis-
Stratum basale – deepest layer
- Main cells are basal cells – single row of stem cells that reproduce to replace keratinocytes that are shed
- __________ cells – sensitive to touch
- Melanocytes – give skin its __________
- Merkel
- color
-5 Layers of the Epidermis-
Stratum __________ – made up of 8-10 layers of keratinocytes that migrate from the stratum basale
1. Cells have lost some cytoplasm – look “spiky” when under a microscope, but spines are not present in life
Spinosum
-5 Layers of the Epidermis-
Stratum Spinosum – made up of 8-10 layers of keratinocytes that migrate from the stratum __________
1. Cells have lost some __________ – look “spiky” when under a microscope, but spines are not present in life
- basale
- cytoplasm
-5 Layers of the Epidermis-
Stratum __________ – “grainy” layer
- Contains keratinocytes from the stratum spinosum
- Cells are undergoing apoptosis – programmed cell death
- Lamellar granules – found within keratinocytes
a. Release lipid-rich secretion
b. Fills in spaces between cells and provides waterproofing
Granulosum
-5 Layers of the Epidermis-
Stratum Granulosum – “grainy” layer
- Contains keratinocytes from the stratum spinosum
- Cells are undergoing __________ – programmed cell death
- __________ granules – found within keratinocytes
a. Release lipid-rich secretion
b. Fills in spaces between cells and provides waterproofing
- apoptosis
- Lamellar
-5 Layers of the Epidermis-
Stratum Granulosum – “grainy” layer
- Contains keratinocytes from the stratum spinosum
- Cells are undergoing apoptosis – programmed cell death
- Lamellar granules – found within keratinocytes
a. Release __________-rich secretion
b. Fills in spaces between cells and provides __________
- lipid
- waterproofing
-5 Layers of the Epidermis-
Stratum __________
- Only present in thick skin
- Cells are flattened, packed together, and full of keratin
Lucidum
-5 Layers of the Epidermis-
Stratum Lucidum
- Only present in __________ skin
- Cells are __________, packed together, and full of keratin
- thick
- flattened
-5 Layers of the Epidermis-
Stratum __________
- Most superficial layer; 20-30 layers of cells
- Made up of dead cells filled with keratin that are tightly connected by desmosomes
- Provides extra protection
Corneum
-5 Layers of the Epidermis-
Stratum Corneum
- Most superficial layer; __________ layers of cells
- Made up of __________ cells filled with keratin that are tightly connected by __________
- Provides extra protection
- 20-30
- dead
- desmosomes
__________ – produce brown/black pigment melanin
- Contributes to skin color and absorbs UV light
- Projections transfer melanin to keratinocytes
- Melanin granules congregate over the nucleus to protect DNA from UV light
Melanocytes
Melanocytes – produce brown/black __________ melanin
- Contributes to __________ color and absorbs UV light
- Projections transfer melanin to keratinocytes
- Melanin granules congregate over the nucleus to __________ DNA from UV light
- pigment
- skin
- protect
Melanin - Color of skin is __________ determined by the number of melanocytes (about the same in all people)
-Determined by the __________ of melanin produced and how long it persists in the keratinocytes
- not
- amount
__________ - Color of skin is not determined by the number of melanocytes (about the same in all people)
-Determined by the amount of melanin produced and how long it __________ in the __________
- persists
- keratinocytes