Lecture 7, part 4 Flashcards
Questions to consider in evaluating cohort studies
How were the study groups selected or defined? (How much selection bias was present?)
Were the data accurate, and was data collection comparable for all study groups? (How much information bias was present?)
How complete was the f/u of both groups?
Were potential confounding factors sought and controlled for in the analysis?
What to consider in evaluation with selection and definition of study groups
Were only ppl at risk of the outcome included?
Was the exposure clear, specific, and measurable?
Were the exposed and unexposed groups similar in all important respects except for the exposure?
What to consider in evaluation with data accurate and comparable data collection
Was the outcome clear, specific, and measurable?
Was the outcome identified in the same way for both groups?
Was determination of the outcome made by an observer blinded as to exposure?
What to consider in evaluation in terms of completion of f/u
What efforts were made to limit LTFU?
Was LTFU similar in both groups?
What to consider in evaluation with confounding factors
Did the investigators anticipate and gather info on potential confounding factors?
What method(s) were used to assess and control for confounding?
