Lecture 6, part 4

Question 1

What question does a pragmatic trial seek answer?

Answer 1

Does an interaction work under usual conditions?

Question 2

Key contextual characteristics of pragmatic trials

Answer 2

Question from and important to stakeholders
Multiple, heterogenous settings
Diverse pops
Comparison conditions
Multiple outcomes important to decision and policy makers
Can assess sustainability of behavior and systems change across the life course

Question 3

Challenges of pragmatic trials

Answer 3

Including broad eligibility criteria introduces greater heterogeneity of pts
Lack of masking/blinding
Pts control changing or discontinuing tx

Question 4

Evaluation design characteristics

Answer 4

Evaluation implemented at either the individual or community/pop level
Choice of comparison group and randomization
Availability of pretest and posttest measures
Timing of the evaluation in relation to intervention
Tyep of analysis