Lecture 7 Flashcards

1
Q

Most important causes for evolutionary change in populations

A

genetic drift and natural selection

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2
Q

genetic drift definition

A

random fluctuations in allele frequencys, no selective pressure so its a random non adaptive change

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3
Q

Genetic drift occurs because natural populations are

A

finite in size

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4
Q

Random fluctuations in allele frequencies can

A

result in non adaptive evolution

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5
Q

natural selection results in

A

adaptive evolution

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6
Q

in genetic drift

A

both conclusions of hardy weinberg equasions have been violated

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7
Q

conclusions of hardy Weinberg violated in genetic drift are

A

allele frequencys changed from generation to generation and genotype frequency were not equal to expect frequency of 0.25 AA+0.5 Aa +0.25 aa=1

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8
Q

Evolution occurs through

A

genetic drift

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9
Q

For genetic drift the alleles included in any generation are

A

a sample of the alleles of the previous generation

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10
Q

all samples are

A

subject to sampling error or random variation

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11
Q

proportions of alleles are likely to differ by

A

change alone, from the proportions they are drawn from

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12
Q

genetic drift is

A

analogous to the null hypothesis in statistics

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13
Q

genetic drift can cause

A

speiciation, without natural selection

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14
Q

way to portray genetic drift

A

a random walk, you start with p=0.5, each generation there’s a equal probability that p will move higher or lower, no stabilizing force so p will wanted to 1 or 0, is fixed 0 is lost

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15
Q

in any given generation alleles are more likely to get lost or fixed in

A

smaller populations

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16
Q

we use the loss of — as a measure of the rate of genetic drift within a population

A

heterozygosity, H=2p(1-p)

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17
Q

As the frequency of one allele approches 1

A

the frequency of heterozygotes declines, rate of inbreeding increases, can lead to interbreeding depression

18
Q

the probability of an allele becoming fixed equals

A

the alleles frequency in the population

19
Q

the allele is more liekly to become fixed in

A

small populations

20
Q

genetic drift proceeds faster in

A

small populations

21
Q

if an allele has just arisen by mutation and is represented by only one among the 2N gene copies in the population its frequency is

22
Q

Census size

A

number of adults we count

23
Q

in actual populations the census size is

A

greater than the number that actually contributes alleles to the next generation

24
Q

in effective population size the

A

rate of genetic drift is greater than would be expected using a populations census size

25
effective population size (Ne) definition
the number of individuals in an ideal population in which the rate of genetic drift would be the same as in the actual population
26
bottleneck
A severe temporary reduction in population size, sometimes occurs when a new population is established by a small number of colonists
27
founder effect
genetic drift in a small colonizing population, if population grows large fast it will not be greatly altered, if it remains small genetic drift will decrease genetic variation and alter allele frequency, new mutations may restore genetic variation
28
consequences of population bottlenecks
fixation of deletreious alleles which reduces survival and reproduction, increasing the extinction risk, and interbreeding depression
29
interbreeding increases
homozygosity and decreases heterozygosity
30
many lethal alleles are
recessive and rare
31
inbreeding increases
homozygosity in individuals that are more liekly to share the same recessive deleterious alleles
32
inbreeding depression
is the reuslting decline in fitness and fecundity that occurs when closely related individuals reproduce
33
inbreeding depression is well known in
small captive populations on endangered species, we have special breeding programs to minimize inbreeding
34
inbreeding also increases risk of extinction of
small populations in nature
35
Neutral theory of molecular evolution definition
the great majority of mutations that are fixed are effectively neutral with respect to fitness and are fixed by genetic drift
36
most genetic variation at the molecular level is
selectively neutral and lacks adaptive significance
37
small minority of mutations in DNA are
advantageous and are fixed by natural selection, many are disadvantoeous and are eliminated by natural selection
38
The neutral theory futher holds that
evolutionary substitutions at the molecular level proceed at a constant rate, so the degree of sequence difference between species can serve as a molecular clock
39
molecular clock
enables us to determine divergence times between species
40
in order to assign concrete dates
the clock must be calibrated by using the fossil record