Lecture 6 - Innate Immunity

Question 1

Functions of immune system?

Answer 1

Protect against infection, recover from infection and tissue damage, maintain adequate relationship with environment

Question 2

Biophysical defence factors?

Answer 2

mucus, cilia lining, stomach acid, skin, lysozymes, gland secretions, commensal organisms, spermine

Question 3

Functions of lymphatic system?

Answer 3

drains leaked fluid from vessels, detects shape changes to alert of a blockage somewhere

Question 4

Cells of the blood and function?

Answer 4

Erythrocytes (O2 and CO2 transport), platelet (clotting factor), neutrophils (phagocytosis, anti-bacteria), basophil (mucosal surface protection), eosinophil (anti-parasite immunity), monocyte (phagocytosis, antigen presentation), lymphocyte (adaptive immunity)

Question 5

Haematopoeisis?

Answer 5

Stem cells differentiate directly into different cell types (incl. RBC, monocytes develop into macrophages in tissue), megakaryocytes which develop into platelets or lymphocytes (into B and T)

Question 6

Primary lymphoid organs?

Answer 6

Thymus, thoracic duct, bone marrow, lymphatic vessels

Question 7

Secondary lymphoid organs?

Answer 7

Adenoids, tonsils, spleen, payer’s patches, appendix, lymph nodes