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Principles of medicine > Lecture 23 - Stem Cells and Regenerative Medicine > Flashcards

Lecture 23 - Stem Cells and Regenerative Medicine Flashcards

1
Q

Stem Cells?

A

self-renewing progenitor cells that can generate one or more specialised cell types

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2
Q

Totipotent Cells?

A

can differentiate into all cell types in an organism

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3
Q

Pleuripotent Cells?

A

Can differentiate into all 3 types of embryonic cells, but not into extra-embryonic tissue

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4
Q

Types of genetic modification?

A

removing genes (knockout), change or insert genes

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5
Q

Methods of genetic modification?

A

homologous recombination, ZFNs, TALEN, RNA-guided nucleases

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6
Q

Considerations for stem cell therapy?

A

Preclinical studies published, approval from independent commitee to ensure low risks, approval from regulatory agency for safe conduct

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Principles of medicine (30 decks)

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