Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

block 15 anna > lecture 6 hepatic pathology > Flashcards

lecture 6 hepatic pathology Flashcards

1
Q

what are lobules

A

small hexagonal functional units

central vein surrounded by 6 portal vein and 6 protal arteries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

how is the hepatic venule connected to surrounding arteries and veins

A

sinusoids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

cell types in the liver

A

kupffer cells
hepatocytes
stellate cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what are kupffer cells

A

macrophages that digest RBCs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what cells line the sinusoids

A

hepatocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

shape of the hepatocytes

A

cuboidal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

stellate cells function

A

in quienscant state they store vit A

when activated they sectere collagen for scar tissue formation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what does the liver do glycogen

A

Storage of glycogen, release of glucose and gluconeogenesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what does the liver do: proteins

A

synthesise e.g. albumin and coagulation factors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what does the liver do: amino acids

A

catabolise amino acids and produces urea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what does the liver do: nitrogenous

A

Detoxification of nitrogenous molecules from the gastrointestinal tract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what does the liver do: bilirubin

A

conjugates and excretes bilirubin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what does the liver do: bile salts

A

produces and excretes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

common cuases of hepatitis

A

alcohol

viral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

hep A transmission

A

feaco-oral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

hep B transmission

A

body fluids, needles, tattoos,

17
Q

hep B risk factors

A

health care worker
sex
IV drug use

18
Q

hep B outer coat

A

HBsAg

19
Q

hep B inner coat

A

HBcAg

20
Q

treatment of hep B

A

vaccine
antivirals
transplant

21
Q

hep C presentation

A

asymptomatic

22
Q

hep C diagnosis

A

difficult

23
Q

transmission of hep C

A

blood
sex
health care work

24
Q

commonest acute viral hepatitis

A

hep E

25
Q

host of hep E

A

pigs

26
Q

fatty liver

A

steatosis

27
Q

what are you at risk of with NAFLD

A

cirrhosis

hepatocellular carcinoma

28
Q

development of liver cirrhosis

A 
Development of fibrosis
Formation of nodules
Loss of hepatocyte microvilli 
Activated stellate cells
Deposition of scar matrix
Loss of fenestrations
Kupffer cell activation
29
Q

complications of hepatic cirrhosis

A

portal hypertension, hepatorenal syndrome, sacites, spontaneous bacterial peritonitis and hepatic encephalopathy

30
Q

what is portal hypertension

A

backup of blood down portal venous system leads to portal hypertension

31
Q

Hepatorenal syndrome

A

Rapid deterioration in kidney function in individuals with cirrhosis or liver failure

32
Q

Hepatic encephalopathy

A

Confusion, altered level of consciousness and coma due to ammonia accumulation

33
Q

pain of hepatocellular carcinoma

A

painless until big

block 15 anna (15 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions