lecture 5 malnutrition and malabsorption Flashcards

1
Q

where is food absorbed into in the GI tract

A

portal vein and thoracic duct

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2
Q

main food

A

carbs 2/3
protein
lipids

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3
Q

kwashikor

A

lack of proteins

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4
Q

Marasmus

A

total dietry lack

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5
Q

Marasmus symtoms

A

apathy, diarrhoea, hepatomegaly, muscle wasting, oedema, anaemia, stomatitis

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6
Q

stomatitis

A

mouth ulcers

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7
Q

anorexia

A

suppression of appetite

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8
Q

what promotes loss of appetite

A

intense cytokine release

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9
Q

inability to swallow

A

dysphagia

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10
Q

what happens to weight in thyrotoxicosis

A

lose weight

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11
Q

commonest malnutrition

A

iron

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12
Q

why might you be iron deficient

A

vegetarian

menses

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13
Q

what anaemia do you get with menses

A

hypochromic

microcytic

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14
Q

where do you find iron

A

red meat

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15
Q

B6 deficiency

A

neuropathy

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16
Q

B1 defcient

A

cardiomyopathy

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17
Q

B2 deficiency

A

stomatitis

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18
Q

niacin deficiency

A

pellagra

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19
Q

pellagra

A

diarrhoea, dermatitis and dementia

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20
Q

folic acid deficiency anaemia

A

megaloblastic

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21
Q

vit D eficiency

A

osteomalacia

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22
Q

who has less cells for Vit D production

A

darker people

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23
Q

B12 deficiency

A

megalosblastic anaemia

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24
Q

SCAD

A

Subacute combined degeneration of spinal cord

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25
Q

B12 deficiency

A

ataxia and dementia

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26
Q

Vit C deficiency

A

scruvy

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27
Q

what happens in scurvy

A

collagen fails to be mineralised properly

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28
Q

Vit K deficient

A

coagulopathy

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29
Q

who gets vitK deficient

A

alcoholics

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30
Q

what is needed for vit D absorption

A

calcium

31
Q

fat soluble vitamins

A

ADEK

32
Q

water soluble vitamins

A

B and C

33
Q

carbs are broken down to

A

polysaccharides

34
Q

where are carbohydrate enzymes

A

on the brush border of the small bowel

35
Q

lack of carbohydrate enzymes

A

lactose intolerant people

36
Q

what are fats broken down into

A

fatty acids and monoglycerides

37
Q

chewing

A

mastication

38
Q

galnds that secrete amylase and lipase

A

parotid, submandibular, submaxillary glands

39
Q

where are protein digesting enzymes

A

stomach

40
Q

what does the chyme pass to get into the small bowel

A

pylorus

41
Q

vagus nerve activity

A

stimulated acetylecholine production
histamine release
lower pH

42
Q

what causes the vagal activity

A

stretch of the food in the stomach

43
Q

hormones produces in the stomach

A

gastrin and histamine

44
Q

what do gastrin and histamine do

A

make parietal cells and the chief cells to increase acid production and pepsinogen enzymes

45
Q

where are pancreatic juices delivered

A

duodenum by the ampulla

46
Q

endocrine function of the pancreas

A

insulin

47
Q

exocrine secretions of the pancreas

A

bicarbonates, secretin and cholecystokinin and enzymes

48
Q

the ducts

A

two hepatic
common hepatic
plus cystic duct
forms common bile duct

49
Q

what isinvolved in the emulsification of fat

A

bile acids

50
Q

what is fat sesnedby

A

cholecystokinin

51
Q

ileum absorbes

A
B12 and intrinsic factor
bile acids (recycles)
52
Q

indigestible thing passed on to the colon

A

starch

53
Q

directionality of enterocytes

A

polarised

54
Q

Giardiasis

A

diarrhoea and bloating

55
Q

whipples

A

villi atrophy

56
Q

what does luminal bacterial overgrowth cause

A

high folate to B12

57
Q

causes of bacterial overgrowth

A

diverticulosis
blind ended loop
motility disorders

58
Q

who might you find a blind ended loop in

A

older people who had peptic ulcer surgery

59
Q

examples of motility disorders

A

diabetes

60
Q

scleroderma

A

connective tissue disorder

61
Q

what do you find gluten in

A

cereal

62
Q

what happens to the villi in coeliac

A

flattened

63
Q

what happens to the crypts in coeliac disease

A

shorten

64
Q

best test for coeliac disease

A

anti tissue transglutaminase antibody

65
Q

what secondary effects does coeliac disease have

A

iron deficiency, folate deficiency and osteomalacia

66
Q

if you have a billiary tract problem what wont be absorbed

A

ADEK

67
Q

ADEK malabsorption

A

coagulopathy, osteomalacia, ataxia, night blindness and xerophthalmia

68
Q

xerophthalmia

A

dry eyes

69
Q

where isintrincic factor produced

A

stomach

70
Q

most common cause of pancreatitis

A

alcoholism

71
Q

what can obstruct the pancreatic duct

A

tumour

72
Q

what do you present with if there is a pancreatic duct tumour

A

jaundice

73
Q

Zollinger ellison syndrome

A

endocrine neoplasia which affects the pancreas