Lecture 5: Smallpox and Influenza Flashcards
What was the first recorded plague? Was it?
- the plague of athens
- ca. 430 BC
What were the symptoms of the plague of athens?
fever, painful skin rash, great thirst
Was there a known treatment for the plague of athens?
no
What resulted from the plague of athens?
athens lost the war
What is the plague of athens suspected to be?
smallpox
Briefly summarize the fall of the aztec empire. Why did it fall?
- Hernando Cortez (Spain), with few than 600 men, conquered the Aztec empire, with a population of several million
- Smallpox broke out among the aztecs 4 months into the battle.
- population lacked inherited or acquired resistances
What is the estimate of how much of the aztec population died from smallpox?
1/4 to 1/3
What does William McNeil argue?
that the reason why the Aztec Empire fell to a few hundred had much more to do with the outbreak of smallpox than other factors.
When and where was the first reported outbreak of smallpox in North America?
In Missouri in 1781
How did smallpox spread in North America?
through the trade routes –> water lines
How many local indigenous treatments attempted to control the spread of smallpox and find a remedy? What is an example of a treatment among the Blackfoot?
- 38+
- eating small bits of the blankets
Smallpox was a ‘___soil’ epidemic.
virgin
Does small pox remain infection outside the body?
yes
Smallpox travels on___carriers.
symptomatic
What was the outbreak of smallpox among plains cree in Canada mitigated by?
vaccines
What did Edward Jenner observe?
That milking maids sometimes developed symptoms that looked similar to smallpox, but which did not progress to smallpox. It seemed, he surmised, that the milking maids had actually contracted some other strain of the disease, cowpox.
After discovering cowpox, what did Jenner wonder?
If humans could be infect with cowpox, and if they might acquire immunity to smallpox
What did Jenner do in his original experiment?
Inoculated an 8 year old boy with cowpox. 6 weeks later he inoculated the same boy with active fluid from smallpox. The boy did not develop smallpox andJenner believed that he had found an effective prevention strategy.
Was the smallpox vaccine helpful? (people still got sick, but they didn’t___.)
die
so it was helpful
What is inoculation?
An older technique that involved exposure to similar diseases, or dead for of the infection.
Who developed vaccination?
Edward Jenner.