Lecture 5 - Protein 2 Flashcards
What is in the protein structure
There are four levels
Primary
Secondary
Tertiary
Quaternary
What happens in the primary structure
Sequence of amino acids in polypeptide chain
What happens in the secondary structure
The polypeptide chain do not remain flat and straight
Hydrogen bonds form between amino acids in the chain
Automatically coil and fold
What could happen is a Alpha and beta pleated sheet - due to the hydrogen bonds depending how they are arranged in the the polypeptide chain
What happens in the tertiary structure
Coiled and folded amino acid chain fold further
More bonds between different parts of the polypeptide chain
Then hydrogen and ionic bonds are formed
Disulfide bridges
What happens in the quaternary structure
Some proteins are made from several different polypeptide chains
Held together by bonds
Is the way the polypeptide chains are assembled together
What is transcription and what happens
Happens in the nucleus in eukaryotic and cytoplasm in prokaryotic cells
DNA is open and helicase goes in
RNA nucleus tides are attached , copies
mRNA is made during transcription
tRNA is complimentry to mRNA
What is translation
Production of polypeptides
Using the sequence of codons carried by the mRNA
Occurs at the ribosome at they cytoplasm
Each unique tRNA molecule will attach to mRNA the complimentary
Once the right amount of amino acid are attached to there is a bond between each amino acid that forms the primary structure of the chain
What do proteins produce
Produce many enzymes
Amylase
Protease
Lipase
Keratin - hair
actin and myosin - muscles
Immunoglobulins
How many codes make up an amino acid
Three dna code make amino acid base
Describe how monomers join to form the primary structure of a protein
There is a condensation reaction between amino acids forming peptide bonds creating a sequence in amino acid
Two proteins have the same number and type of amino acids but different tertiary structures
There are different types of bonds within different places
Different primary structure and different sequence of amino acids