Lecture 3 Flashcards
how many cases of cutaneous leish
300 millions
how many cases of visceral leish
50 million cases
where are 50% of the visceral leish cases
mostly in bihar, nepal and bangladesh
true or false in an 100 years most of the cases of leish are still at the same spot
true
true or false: multiple amastigotes can infect the same macrophages
true
how many days does it take for a cycle of leishmania in the sandfly
8 days
true or false: it is the male sandfly that bites
false it is the female sandfly that bites cuz she needs the nutrients
how long does a sandfly lives
20 days
amastigotes first convert into the …. stage and rapidely multiply in the midgut
procyclic
procyclic converts to the … stage then to … in the thoracic midgut
nectomonad and leptomonad
leptomonads convert to…. that are the human infective stage and takes….. days
metacyclics and takes about 6-8 days
how does the sandfly gets the blood
-when it bites it chops the skin to draw the blood out
-then it secretes the amastigotes there
true or false leish only infects macrophages
false it also infects neutrophils
the leish cutaneous lesions are caused by what
the immune response
true or false: cutaneous leish only replicates in the macrophages
true