Lecture 23: Embryology, Pregnancy and Child Birth Flashcards

0
Q

Spermatozoa viable for how many hours in female tract?

A

48 hours

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1
Q

Oocytes viable for how long?

A

12-24 hours

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2
Q

Sperm must be undergo what? takes 6-8 hours after ejaculation.

A

Capacitation

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3
Q

Once a single sperm binds to oocyte plasma membrane a reaction occurs to exclude what?

A

All other sperm

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4
Q

Blastocyst implants into endometrium by secreting what, onto the endometrial surface?

A

digestive enzymes, cytokines and growth factors

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5
Q

Trophoblast cells secrete what substance which is measured in urine to test for pregnancy.

A

human chorionic gonadotrophin

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6
Q

hCG prompts corpus luteum to keep secreting what, until

placenta takes over?

A

progesterone

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7
Q

Placenta makes and secrete what two hormones for the remainder of pregnancy until birth?

A

oestrogen and progesterone

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8
Q

Chorionic villi project from fetal tissue into maternal

blood vessels to form what two structures?

A

umbilical arteries and vein

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9
Q

Placenta =

A

chorionic villi + decidua basalis

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10
Q

The umbilical vein during pregnancy does what?

A

oxygenated blood => mother=>placenta =>Fetus

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11
Q

The umbilical artery does what during pregnancy?

A

deoxygenated blood + waste => fetus =>placenta =>mother

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12
Q

What are the four Embryonic membranes:

A
  • AMNION
  • YOLK SAC
  • ALLANTOIS
  • CHORION
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13
Q

Name the 3 primary germ layers:

A
  • ECTODERM
  • MESODERM
  • ENDODERM
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14
Q

What do the three germ layers contain?

A

Ectoderm => epidermis, nervous system

Mesoderm => smooth muscle, connective tissue, blood vessels, blood cells, skeleton, skeletal muscle, reproductive and excretory
organs.

Endoderm => epithelial linings of respiratory passages and digestive tract.

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15
Q

Neuroectoderm forms what two structures?

A

Brain and spinal cord

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16
Q

Neural crest cells form what?

A

dorsal root (sensory) ganglia of spinal and cranial nerves.

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17
Q

What do Somites form?

A

axial skeleton + adjacent muscles + dermis.

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18
Q

As the embryo folds it encloses part of the yolk sac

that goes on to develop into what structure?

A

digestive tube

19
Q

Endodermal tube forms the EPITHELIAL LININGS of what 3 structures?

A

Digestive system, respiratory systems and associated glands

20
Q

Intermediate mesoderm forms what?

A

gonads, kidneys, adrenal cortex

21
Q

Lateral somatic mesoderm form what?

A

dermis, peritoneum, limb buds

22
Q

Lateral splanchnic mesoderm forms what?

A

cardiovascular system organs, connective tissues, all but

epithelial lining of digestive and respiratory organs.

23
Q

Blood supply to the foregut ( epigastric )?

A
Coeliac artery (except pharynx, respiratory tract,                              
most of oesophagus)
24
Q

Midgut ( umbilical) derivatives

A
  • Small intestines (inc. most of duodenum)

* Caecum, vermiform appendix, ascending colon, right 1⁄2 - 2/3 of transverse colon.

25
Q

Blood supply to the midgut (umbilcal) derivatives

A

Superior mesenteric artery

26
Q

Hindgut (hypogastric) derivatives

A
  • Distal part of transverse colon, descending colon, sigmoid colon, rectum, anal canal.
  • Epithelium of urinary bladder and most of urethra.
27
Q

Blood supply to the hindgut derivatives?

A

Inferior mesenteric artery

28
Q

4thweek of development – ventral and dorsal buds from?

A

Foregut

29
Q

By the end of the 6th week, the rotation of the duodenum has brought ventral and dorsal buds together to?

A

Fuse

30
Q

Ventral bud forms what?

A

head and uncinate process.

31
Q

Dorsal bud forms what?

A

Neck, body and tail

32
Q

Endoderm of primitive gut gives rise to most of the what?? of the digestive tract.

A

epithelium and glands

33
Q

Epithelium from cranial and caudal extremities is

derived from the ?

A

ectoderm of the stomodeum

34
Q

Muscular and connective tissue components of

digestive tract are derived from the?

A

splanchnic mesenchyme surrounding primitive gut.

35
Q

4 weeks gestation:
Signals from heart trigger underlying endoderm to generate primary liver bud as an outgrowth of the ventral wall of the? .

A

FOREGUT

36
Q

Five Months

A protective coating begins to form on baby’s skin, what is it called?

A

vernix caseosa

37
Q

By 4th month the uterus fills the?

A

pelvis

38
Q

By 9th month the fundus of the uterus is at the level of the?

A

xiphoid process

39
Q

Abdominal organs are pushed superiorly under the?

A

diaphragm.

40
Q

Coccyx permitted to move more posteriorly to increase?

A

pelvic outlet

41
Q

Conjugate distance between sacral promontory and

posterosuperior aspect of pubic symphysis is?

A

Fixed

42
Q

Transverse diameter & amount of pelvic rotation permitted around sacrum is increased due to?

A

effect of relaxin hormones on pelvic ligaments

43
Q

Back pain in pregnancy

A
  • Increased maternal weight spine.
  • Referred pain from visceral compression.
  • Direct compression on exiting nerve roots in pelvis.
  • Venous congestion in pelvis and lumbar spine from uterus compression inferior vena cava.
  • Relaxin hormone causing ligamentous laxity.
  • Pelvic instability.
44
Q

What is the let down reflex?

A

oxytocin binds to myoepithelial cells surrounding alveoli –>
milk ejected form alveoli into ducts from both breasts