Lecture 20 Flashcards
Innate Immunity
Non-specific, General response to an invasion, acts immediately upon invastion
Adaptive Immunity
Takes a week or two to develop, discriminates between infecting organisms and self and non self, has memory-quicker response to reinfections
Self vs non-self
Self= itself. Non-self= foreign cell
Immune memory
Quicker response to reinfections
Physical Immune Barries
Skin, mucous membranes, normal flora
Gamma-delta T-cells
Small subset of T cells that possess a distinct T-cell receptor on their surface
Leukocyte
Granulocytes produce cytokines. Phagocytes eat pathogens
Granulocyte
Produce cytinkines
Cytokine
a diverse group of soluble proteins, peptides, or glycoproteins which act as humoral regulators or signaling molecules
Chemokine
a family of small cytokines, or signaling proteins secreted by cells.
Interlyukin
Communication between leukocytes
Interferon
proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites or tumor cells
Tumor necrosis factor
Kills tumor cells (apoptosis)
Phagocyte
Important to destroy most invading microbes
PMN (neutrophil)
he most abundant type of white blood cells in mammals and form an essential part of the innate immune system.
Monocyte
Macrophages, dendritic cells