Lecture 19 Flashcards
Spike Protein
Glyco proteins or envelope proteins. Peptides and proteins that regulate the activity of TRANSCRIPTION FACTORS and cellular processes in response to signals from CELL SURFACE RECEPTORS.
Matrix Protein
Required for replication. In some viruses they may be closer to the nucleocapsid then shown in the diagram.
Capsid (nucleocapsid)
Protein
Capsomere
basic subunit of the capsid, an outer covering of protein that protects the genetic material of a virus.
Nucleic Acid
DNA or RNA
Viral-associated proteins
Replication of nucleic acid
Plaque Assay
Holes on the plate. viruses are grown on tissue cultures and appear as this if they lyse the hose cell. it replicates and lyses the cell
Baltimore classification system
They way viruses are classified. Based on nucleic acid. Classified by roman numerals
Helical/ lcosahedral/ Complex
They shape of the virus particle. Helical- circular. Icosahedral- 3D triangles are put together. Complex-phage
Attachment/ Membrane receptors
Attachment of viral proteins “spikes” to glycoprotein receptors on host membrane
Membrane Fusion
This is for if it is an enveloped virus. It is how the virus enters the cell
Uncoating
Vital nucleic acid separated from protein coat
Virion assembly/maturation
Assembly of new virus particles
Polyprotein
One big protein that has to be cut into the correct pieces by protease
Protease
Crops up the protein