Lecture 11: Skeletal System Flashcards
Bone classification
Long: femur, humerus
Short: talus, digits
Flat: cranium, scapula
Irregular: vertebrae
Functions of skeletal system
Support Protection Movement Blood cell production Mineral storage Lipid storage
Anatomy of a long bone
Periosteum: CT covering
Epiphysis: ends
Diaphysis: shaft
Epiphyseal plate: cartilage where growth occurs
Articular cartilage: joints
Medullary cavity: inside diaphysis, stores marrow
Bone cells
Calcification
Osteoblasts: build then become osteocytes and maintain bone
Osteocytes: mature bone cell
Osteoclasts: break down bone
Compact bone tissue
Haversion system (osteon): central canal
Lacunae: space between lamellae that cell sits in
Canaliculi: transports nutrients between osteocytes and Haversion canal
Lamellae: concentric layers surrounding Haversion canal
Trabeculae
Boney bars
Bone formation
Endochondral ossification: formed cartilage mold
Cartilage model dvlpmt: chondroblasts make cartilage mold
Growth of cartilage model: chondroblasts become chondrocytes and divide
Primary/secondary ossification center: cartilage converted to bone by osteoblasts
Articular cartilage and epiphyseal plate formation: cartilage remains at ends and epiphyseal plates
Bone growth
Length (interstitial): cartilage cells divide and turn into bone
Thickness (appositional growth): blood vessels in periosteum are surrounded and become Haversion canal
Calcium
Parathyroid hormone (PTH): stimulates osteoclasts, kidneys retain calcium
Calcitrol: released by kidneys, GI tract retains calcium
Calcitonin: inhibits osteoclasts, osteoblasts build faster