Lecture 10 Chapter 18 Flashcards
What characteristics have a low reticulocyte and high/increased MCV
Megaloblastic/macrocytic
Macrocytic anemias effect
Production of DNA
What is the first step when examining a blood smear
Look at reticulocytes and MCV
What happens if you cannot synthesize thymine
Cannot produce thymidine → cannot make DNA → cells grow extra because they want to divide but cannot without enough thymidine
What WBC commonly cannot divide due to lack of thymidine
Hypersegmented neutrophil
What is a common cause of macrocytic anemias
Vitamin deficiency of b-12 and folic acid
Hypersegmented neutrophil
What do you do if you are uncertain if a segmented neutrophil is hypersegmented
Do not report it unless certain
Symptoms/signs of megaloblastic anemia
Hypersegmented neutrophil
Ovalocytes
Decreased MCH
MCV may be 120
MCHC normal
Where are vitamins stored in your body
Liver
How much folate do you normally have stored
About enough for 1 week
How long is b-12 stored for
About 1 year
What food has the highest source of folate
Vegetables
What is the only source of b-12
Animal products, red meat, meat
Why must a pregnant woman take folate supplements
Folic acid deficiency in a pregnant woman will severely effect the fetus. Prevents the spinal cord from closing, most likely paralyzing the child