Lectrue1C Flashcards
What two things propagate the action potential in a cardiac muscle cell?
the sarcolemma and the t-tubules
What is happening during the UNIQUE plateau during the myocyte action potential?
Ca2+ channels are opening and Ca2+ rushes in from the ECM
What does the ECM Ca2+ rush in from the ECM trigger within the cell?
Ca2+ release from the sarcoplasmic reticulum! even more Ca2+!!
What determines the magnitude of power by the myofibril?
Amount of Ca2+ available!
What about the sarcoplasmic reticulum is different in cardiac muscle from skeletal muscle?
Its less dense (c/o the ECM Ca2+ that rushes in)
What about the number of mitochondria is different in cardiac muscle from skeletal muscle?
Cardiac has MUCH more!
What are the two components to intercalated discs? Functions?
- Desmosomes (prevent separation) 2.Gap Junctions (free ion depolarizing current)
What is the term for myocardium behaving as a single coordinated unit?
Functional SynCyTium
What are the three proteins of the cardiac Troponin?
T.I.C T-Tropomyocin binding I-Inhibitory C-Calcium binding
What is the difference between Angina and M.I.?
Angina-cells live….M.I.-cells die
How can you tell the difference between angina and M.I.?
Angina goes away with NitroGlycerin treatment
What are the markers for a M.I.?
Troponin I
