4A-MicroCirculation/EDEMA Flashcards
What is the major function of the capillary network?
nutrient/waste exchange w/ tissues
Where is lymph created?
intersitial spaces
What is the ultimate fate of lymph?
put back into circulation
Do lymph vessels have valves?
YES
What are the three methods of exchange?
1.Diffusion 2.fenestrations 3.pinocytosis
What are Pc Pi Pi-c and Pi-i collectively called?
Starling forces
What is Pc?
Capillary hydrostatic pressure
What it Pi?
Intersitial hydrostatic pressure
What is Pi-c?
Capillary oncotic (protein) pressure
What is Pi-i?
Interstitial oncotic (protein) pressure
Which two starling forces do we typically ignore?
P-i and Pi-i (usually undergo negligible changes)
Who wins the tug of war on the arterial/filtration end? P-c or Pi-c?
P-c wins (higher [fluid] inside capillary)
Who wins the tug of war on the venous/absorption end? P-c or Pi-c?
Pi-c (higher [protein] inside the capillary) allows it to pick up wastes
Since a net of +6 leaves the arterial capillary and a net of -5 gets picked back up, what happens to the excess fluid?
Lymph picks it up!
What are the two end ducts for lymph? what side of the body?
Right Lymphatic Duct & Left Thoracic Duct
Which veins ultimately collect ALL the lymph?
Left and Right Subclavian veins
Which duct receives lymph from the lower extremities?
Thoracic duct and therefore left subclavian…Interesting picture!
What are lymph nodes essentially compared to?
FILTERS!
What type of edema do you palpate and the tissue does not rebound?
pitting edema
BOOOM big concept! What are the 4 causes of edema?
- Excess filtration (HIGH P-c) 2.Decreased absorption (LOW Pi-c) 3.Increased capillary permiablilty 4.blocked lymphatics
