4A-MicroCirculation/EDEMA

Question 1

What is the major function of the capillary network?

Answer 1

nutrient/waste exchange w/ tissues

Question 2

Where is lymph created?

Answer 2

intersitial spaces

Question 3

What is the ultimate fate of lymph?

Answer 3

put back into circulation

Question 4

Do lymph vessels have valves?

Answer 4

YES

Question 5

What are the three methods of exchange?

Answer 5

1.Diffusion 2.fenestrations 3.pinocytosis

Question 6

What are Pc Pi Pi-c and Pi-i collectively called?

Answer 6

Starling forces

Question 7

What is Pc?

Answer 7

Capillary hydrostatic pressure

Question 8

What it Pi?

Answer 8

Intersitial hydrostatic pressure

Question 9

What is Pi-c?

Answer 9

Capillary oncotic (protein) pressure

Question 10

What is Pi-i?

Answer 10

Interstitial oncotic (protein) pressure

Question 11

Which two starling forces do we typically ignore?

Answer 11

P-i and Pi-i (usually undergo negligible changes)

Question 12

Who wins the tug of war on the arterial/filtration end? P-c or Pi-c?

Answer 12

P-c wins (higher [fluid] inside capillary)

Question 13

Who wins the tug of war on the venous/absorption end? P-c or Pi-c?

Answer 13

Pi-c (higher [protein] inside the capillary) allows it to pick up wastes

Question 14

Since a net of +6 leaves the arterial capillary and a net of -5 gets picked back up, what happens to the excess fluid?

Answer 14

Lymph picks it up!

Question 15

What are the two end ducts for lymph? what side of the body?

Answer 15

Right Lymphatic Duct & Left Thoracic Duct

Question 16

Which veins ultimately collect ALL the lymph?

Answer 16

Left and Right Subclavian veins

Question 17

Which duct receives lymph from the lower extremities?

Answer 17

Thoracic duct and therefore left subclavian…Interesting picture!

Question 18

What are lymph nodes essentially compared to?

Answer 18

FILTERS!

Question 19

What type of edema do you palpate and the tissue does not rebound?

Answer 19

pitting edema

Question 20

BOOOM big concept! What are the 4 causes of edema?

Answer 20

1. Excess filtration (HIGH P-c) 2.Decreased absorption (LOW Pi-c) 3.Increased capillary permiablilty 4.blocked lymphatics