Inclass Activity-Anti-Hypertensive DRUGS!

Question 1

How does a diuretic lower BP?

Answer 1

Makes you urinate and causes less blood volume=less BP

Question 2

What is the difference between Propanol and Metoprolol?

Answer 2

Both Beta blockers, but Propanolol=non selective…Met=Beta-1 receptor blocker ONLY!

Question 3

How do beta blockers reduce BP?

Answer 3

Block the sympathetic NS from acting on the heart=lessSV=less CO=less BP

Question 4

How do ACE inhibitors lower BP?

Answer 4

block angiotensin I—->angiotensin II therefore no vasoconstriction, no ADH release, no Aldosterone, no thirst, no retention of H20=low BP

Question 5

How does an angiotensin receptor blocker lower BP?

Answer 5

Angiotensin II is blocked from stimulating ADH release, aldosterone release, kidney sodium retention, and vasoconstriction

Question 6

How does a DRI lower BP?

Answer 6

Direct Renin Inhibitor stops Angiotensinogen–>angiotensin I. This will reduce vasoconstriction, ADH release, Aldosterone release, and the kidney will not retain water.= lower BP

Question 7

How does the oldie CCB work to lower BP?

Answer 7

Calcium Channel Blocker- direct correlation between [Ca2+] and myocardium force. Lowering Ca2+ will lower the force generated by the heart

Question 8

What is the difference between the CCBs Amlodipine and Diltiazem?

Answer 8

Amlodipine is a calcium channel blocker in the HEART only! diltiazem is a CCB in the entire body