LEC 5

Question 1

def? decreased O2 carrying capacity of blood, due to either insufficient Hb or abnormally functioning Hb

Answer 1

anemia

Question 2

what are the symptoms of anemia

Answer 2

fatigue and shortness of breath

Question 3

what kind of anemia has pts that crave unusual substances

Answer 3

IDA

Question 4

if anemia is asymptomatic what does that tell you

Answer 4

slow progression

Question 5

what will be on the skin of people with anemia

Answer 5

petechiae

Question 6

what will pts with anemia eyes look like (3)

Answer 6

pallor, jaundice, or hemorrhage

Question 7

what will pts with anemia mouth look like

Answer 7

mucosal bleeding

Question 8

what will pts with anemia heart do

Answer 8

have cardiac murmurs or arrhythmias

Question 9

t or f: people with anemia will have sternal tenderness

Answer 9

t

Question 10

describe someone with asymptomatic anemia heart beat

Answer 10

normal

Question 11

what happens in ineffective erthropoiesis

Answer 11

• erythroid precursors are defective
• most cells die the BM

Question 12

what is the issue with megaloblastic anemia, thalassemia, sideroblastic anemia

Answer 12

ineffective erythropoiesis

Question 13

what happens in insufficient erythropoiesis

Answer 13

number of erythroid precursors produced in BM is low

Question 14

what will increase in a pt treated with anemia in 7-10 days

Answer 14

reticulocytes

Question 15

what does MCHC tell you about anemia

Answer 15

type

Question 16

what does RDW tell you about anemia

Answer 16

if retics are present

Question 17

if someone has anemia what is found in a urine test

Answer 17

Hb

Question 18

_____ is often a symptom of another disease

Answer 18

anemia

Question 19

what kind of cell size? MCV < 80 fL

Answer 19

microcytic

Question 20

what kind of cell size? MCV > 100 fL

Answer 20

macrocytic

Question 21

what kind of cell size? MCV 80 - 100 fL

Answer 21

normocytic

Question 22

morphology? hemolytic anemias

Answer 22

normocytic/normochromic

Question 23

what type of anemia is the most common microcytic hypochromic

Answer 23

IDA

Question 24

morphology of megaloblastic and non-megaloblastic anemia

Answer 24

macrocytic/ normochromic

Question 25

what type of anemia has BM failure

Answer 25

aplastic

Question 26

what groups are most at risk for IDA

Answer 26

menstruating women, pregnancy, and breast feeding

Question 27

what disease would have these test ordered: evaluation of heme synthesis, free erythrocyte protoporophyrin, soluble transferrin receptor, and BM evaluation

Answer 27

IDA

Question 28

what is the problem with heme synthesis

Answer 28

abnormality of heme synthesis

Question 29

morphology of sideroblastic anemia

Answer 29

microcytic and hypo chromic

Question 30

def? accumulation of iron in mitochondria around the nucleus

Answer 30

ringed sideroblast

Question 31

what chromosome is linked to sideroblastic anemia

Answer 31

X

Question 32

what disorder will lead to sideroblastic anemia

Answer 32

lead poisoning

Question 33

what accumulates in heme synthesis of sideroblastic anemia pt

Answer 33

ALA, iron, and protoporphyrin

Question 34

what is the diff between pappenheimer bodies and sideritic granules

Answer 34

can not see all sideritic granules in wright stain

Question 35

what kind Hb is increased in beta thalassemia minor

Answer 35

Hb A2

Question 36

IDA stage?
- iron stores are depleted
- RBCs not effected

Answer 36

stage 1

Question 37

IDA stage?
- RBCs are produced with not the proper amount of Hb

Answer 37

stage 2

Question 38

IDA stage?
- IDA has developed
- symptoms are present

Answer 38

stage 3