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Question 1

Act as erythrocytic parasites?

Answer 1

Blood schizonticides

Question 2

Types of lice?

Answer 2

• Pediculus Humanus Capitis
• Corporis
• pubis crabs bro

Question 3

Examples of Nematodes?

Answer 3

• Hookworm disease
• Ascariasis
• Enterobiasis
• Filariasis-Riverblindness, Loa loa, Lymphatic (can live there)

Question 4

What are the antimilarial drugs?

How are these administered?

Answer 4

• Quinolines
• Atovaquone
• Artemisinins

Either prophylactically or as definite therapy

Question 5

Artemisinin is a?

How does it work?

Answer 5

Antimalarial medication

• Its a sesquinterpene lactone endoperoxide

Question 6

Name the quinolines

What are there adverse effects and how do they work?

Answer 6

Chloroquine, Mefloquine, Quinine, Primaquine

• Hematologic abnormalities, hemolysis, prolonged QT, hypotension
• Quinine can cause cinchonism, tinnitus, headache, nausea, dizziness, flushing, visual disturbances

Question 7

Metronidazole? And Tinidazole

How does it work?

What is it good at fighting against?

AE?

What are its three functions of killing?

Answer 7

Amebicide

Does a ton of things, it kills trophozoites but not cysts by causeing DNA damage.

Good for kill Clostridium

Kills: Amebiasis, Giardiasis, Trichomoniasis

Dry mouth, nausea, metallic taste

Amebicidal, bactericidal, Trichomonicidal

Question 8

Albendazole?

MOA?

Used for?

Answer 8

Antihelminthic

• Inhibits the polymerization of microtubules
• Intestinal parasites: Cysticercosis, Acariasis, Enterobiasis (pinworm)
• Hydatid disease (Echinococcus via dogs)
• Neurocysticercosis

Question 9

Flatworms examples?

Answer 9

• Neuro Cysticerosis
• Schistosomiasis blood flukes?

Question 10

Kill sexual stages and prevent transmission to mosquitos?

Answer 10

Gametocides

Question 11

What can lice transmit?

As a result causes?

Answer 11

Rickettsia promazekii

Louseborne typhus

Question 12

Ivermectin?

MOA?

Used in?

Answer 12

Antihelminthic

• Causes paralysis by intensifying GABA-mediated transmission of signals in peripheral nerves crazy
• Onchocerciasis: River blindness
• Microfilaria
• Ectoparasites such as scabies

Question 13

Scabies?

Answer 13

Carcoptes scabei

Question 14

Sexually transmitted parasitic infection?

Only one gone over in class

What does it stick to and damage?

Answer 14

Trichomoniasis

• Adheres to and damages squamous epithelial cells
• coexists with gonorrhea

Question 15

Eliminate developing or dormant liver forms?

Answer 15

Tissue schizonticides

Question 16

Amebiasis

Most important?

Causes?

Can cause what type of liver disease?

Answer 16

• most important parasitic disease
• Causes dysentary as a result of cytotox. on colonic epithelial
• Can also cause amebic liver disease

Question 17

What is pentamidine?

What is it used in?

Whats else?

Answer 17

• Used in african Trypanosomiasis - Sleeping sickness
• Leishmaniasis
• Its highly toxic

Question 18

The most common cause of water borne disease in the US?

Answer 18

Giardiasis

Question 19

What is the oldest and highly effective antimalarial blood schizonticide?

Answer 19

Quinolines