Infections Slide set 5 Flashcards
What are the 6 bacteria types?
- True Bacteria
- Filamentous Bacteria
- Spirochetes
- Mycoplasmas
- Rickettsia
- Chlamydia
Miroorganism/human relationship
Mutual relationship - Normal Flora - Relationship can be breached by injury + Leave their normal sites and cause infection elsewhere
Bacterial virulence and infectivity.
Bacteria must have iron to multiply (Siderophores) - Presence of polysaccharide capsules - Supression of complement activation - Bacterial proliforation rates can surpass protective response.
Bacteria can produce endotoxins and exotoxins whats the difference?
Endo- lipopolysaccharides contained in the cell walls of gram negative organisms. Pyrogenic effects Exo- Enzymes released during growth causing specific responses - Immunogenic - Antitoxin production.
Bacterial Sepsis? Associated with?
ARDS, DIC, Hemodynamic effects and renal failure.
Staphylococcus aureus is?
Gram positive bacterial sepsis.
Bacteremia or septicemia
- Presence of bacteria in the blood due to a failure of the body’s defense mechanisms
- Usually caused by gram-negative bacteria
- Toxins released in the blood cause the release of vasoactive peptides and cytokines that produce widespread vasodilation
Respiratory infections: Pneumonia
Community acquired
Pneumococcal pneumonia (strepto pneumoniae)
Mycoplasm in young
Nosocomial Infection?
Pneumonia
Staph aureus, Kleb pneumoniae, P. Aeroginosa
Immunocompromised patients?
Pneumonia
P. Jiroveci
Pneumonia Port of Entry
- Aspiration of oropharyngeal secretions
- Inhalation of aerosols
- From blood bacteremia
Explain how Pneumococcal Pneumonia gets in and infects the body?
Respiratory Infections TB or Mycobacterium Avium complex
TB has the ___ death toll of any infectious pathogen
POA:?
TB—?
MAC in what type of patient?
How to detect TB?
- Highest death toll
- Airborne transmission
- Mycobacterium tuberculosis
- MAC in immunocompromised patients
Detected
- Tubercle formation
- Caseous necrosis
- Positive tuberculin skin test (PPD)
Respiratory Infections: Acute bronchitis
What is it?
Bronchitis causes similar symptoms as? But doesnt demonstrate what?
- Acute inflammation or infection of the airways or bronchi
- Symptoms like pneumonia but doesnt demonstrate pulmonary consolidation and chest infiltrates
Respiratory Infection: Acute epiglottitis
Most common in?
WHat happens how serious?
What bacteria causes it?
Symptoms?
Treatment?
- Children
- Severe rapid progressive, life threatening infection of the epiglottis and surrounding area
- Usually cause by Haemophilus influenzae type B
- Incidence decreased by HIB vaccine
- High fever, sore throat, inspiratory stridor, sever respiratory distress
- Emergency airway and antibiotics