Laboratory Diagnostics BLOCK 6 Flashcards
What do laboratory diagnostics test for
Test body fluids for bio chemicals/ hormones/ drugs
What is the routine chemistry in blood test
- glucose
- calcium
- proteins
- electrolytes
- kidney test
- liver tests
- cardiac tests
- lipid panel
What is tested for diabetes in blood
Glucose mellitus
What is part of BMP?
Glucose
Calcium
Electrolytes
Kidney tests
What detects renal function in blood test?
BUN/creatinine (creatinine better)
What detects liver damage in blood
ALT, AST, ALP
What detects liver function in liver
Bilirubin
What does it mean when there is increased bilirubin in blood
Decreased function
What are parts of the CBC
- WBC
- hemoglobin and hematocrit
- RBC
- platelet count
- WBC differential
Increased WBC in blood count
Infection/inflammation
Decreased hemoglobin and hematocrit in CBC
Anemia
What does neutrophilia in CBC detect?
Bacterial infection
What does lymphocytosis suggest in CBC
Viral
What does eosinophilia suggest in CBC
Allergies or worms
Blood disorders
- anemia
- polycythemia
- leukemia
- thrombocytopenia
What happens when there is a 4x change or more in titers?
Acute
Tests for antigens and antibodies
IgM (acute)
IgG (convalescent)
What does it mean if Anti-HBs is present in blood
They are vaxxed
What is the only Ab that protects from Hep-B?
Anti-Hbs
What clears when someone is immunized for Hep-B
Anti-HBsAg
What slows Hep B?
Anti-HBeAg
What PROVES Hep B infection
Anti-HBcAg
What is the only condition where treatment comes from blood bank and not pharmacy?
Hemophilia A, factor 8
What are the only numbers that should show up in a healthy CBC
Specific gravity and pH
What is the most common finding in urinalysis for UTI?
Leukocyte esterase
What all could you see in UTI CBC?
- leukocyte esterase
- WBC
- blood
- protein
- nitrite
Amount present does not determine how bad infection is
What does presence of ketones indicate in CBC
Diet/starvation indicator
Reliability of medical tests
All medical tests are flawed
Positive and sick
True positive
Positive and healthy
False positive
Healthy
True negative
Sick and test says otherwise
False negative
Accuracy
Is it correct
Is this reproducible?
Precision
Sensitivity
Sick people
Specificity
Heathy people
Disease is present and test is negative
False negative
Disease is present and test is positive
True positive
Disease absent, tests positive
False positive
Disease absent, lab test negative
True negative
Sensitivity about _______ people testing ________
Sick people testing positive
What is the equation for sensitivity
TP/(those with disease)= TP/(TP + FN)
Specificity is about ______ people testing _________
Healthy people testing negative
Equation for specificity
TN/(TN +FP)