L9 Flashcards
What is the innervation to the dilator muscle of the iris? What is the result? What is the NT and receptor?
Sympa -> dilate
NE on alpha 1 receptor
If you have an ocular sympathetic lesion, what would you see?
Normal = dilate Lesion = miosis (Horner's)
What is the innervation to the sphincter muscle of the iris? What is the result? What is the NT and receptor?
Para -> constrict
ACh on M3 receptors
If you have an ocular para lesion, what would you see?
Blown pupil (dilation)
What drug do you use to dilate pupil for lazy eyes?
Atropine
What would the effect of alpha1 agonist eyedrops be? What is the drug?
Phenylephrine
- Activate sympa –> dilation
What would the effect of a cholinergic antagonist be? What is the drug?
Tropicamide
Antagonize sphincter muscle activation - prevent miosis
Drugs that dilate your eyes
Atropine = muscarinic antagonist Phenylephrine = a1 agonist Tropicamide = cholinergic antagonist
What drug do you use to reverse dilation you just cause via drugs?
Dapiprazole = alpha blocker
What are the SC of sympathetic overload?
“Mad as a hatter, dry as a bone”
Dry skin, mouth + constipation + urine retention
Irritable, delirious
Tachycardia
1 blown pupil differential
Intracranial pathology
Or you accidentally touched your eye with dilator
Define glaucoma
Optic disc atrophy due to death of ganglion cells
What is the only treatable risk factor for glaucoma?
↑IOP
4 types of glaucoma
- Open angle - dilation makes better
- Angle closure - dilation causes acute angle closure attack
- Secondary
- Childhood
Where is this angle we’re talking about
Bet iris & cornea