L6: HTN (Pt 4) Flashcards
Def of Resistant HTN
Etiology of Resistant HTN
Etiology of Resistant HTN
- Meds
- Inadequate doses
- Drug actions and interactions (e.g., (NSAIDs)
- illicit drugs, sympathomimetics, OCP
- Over-the-counter drugs and some herbal supplements
TTT of Resistant HTN
Def of Pseudoresistant HTN
Causes of Pseudoresistant HTN
Def of Hypertensive Emergency
Def of Hypertensive Urgency
Severe elevation of BP (DBP > 115) WITH No progressive end-organ disease
Hypertensive Emergency
- CNS
Hypertensive Emergency
- CVS
Hypertensive Emergency
- Renal
Cerebral Autoregulation
Therapeutic considerations in hypertensive emergencies
Therapeutic considerations in hypertensive emergencies
- Potential Complications of Therapy
Therapeutte considerations in hypertensive emergencies
- Initial Lowering of BP (Therapeutie Guldelines)
- High BP WITHOUT acute end-organ dysfunction IS NOT a hypertensive emergency and called “Hypertensive Pseudoemergency
….
TTT of Hypertensive Emergencies
- …….have been available for years and are preferred in most conditions.
- Labetalol and esmolol
TTT of Hypertensive Emergencies
- Nitroglycerin and sodium nitroprusside have also been widely available, but their use is limited primarily to individuals with ……
- myocardial ischemia
- acute pulmonary edema
- acortic dissection
TTT of Hypertensive Emergencies
- third-generation agent …….., represents the first agent for hypertensive emergency to be introduced
Clevidipine
Pharmacologic TTT of Hypertensive Emergency
- Nitroprusside
- Nitroglycerin
- Nifidipiine
- Labetalol
- Diazoxide
- Hydralazine
- ACEis
- Fenoldopam
- Nicardipine
Pharmacologic TTT of Hypertensive Emergency
- Nitroprusside (MOA, Value, SE)
Pharmacologic TTT of Hypertensive Emergency
- Nitroglycerin (MOA, Value)
Nitroglycerin and Nitroprusside in HTN Emergency
- Adv
- SE
- Dosing & Monitoring
Pharmacologic TTT of Hypertensive Emergency
- Nifidipine (MOA, Onset, SE)