L5: Infective Endocarditis Flashcards
Def of Infective Endocarditis
RF for Infective Endocarditis
Etiology of Infective Endocarditis
Etiology of Infective Endocarditis
- Source of Infection
Etiology of Infective Endocarditis
- Causative Organsims
Etiology of Infective Endocarditis
- Cardiac Lesions
Etiology of Infective Endocarditis
- Most common Organism
Strep. Viridians
Etiology of Infective Endocarditis
- Most Virulent Organism
Staph aureus
Etiology of Infective Endocarditis
- Staph epidermedis
- accounts for 30% of cases of PVE (prosthetic valve endocarditis
Etiology of Infective Endocarditis
- Fungal Infection
(In I.V drug addicts)
Etiology of Infective Endocarditis
- Gram -ve Organisms
(After urinary procedures )
Etiology of Infective Endocarditis
- HACEK
Valves affected in Infective Endocarditis
Pathogenesis of Infective Endocarditis
Classification of Infective Endocarditis
CP of Infective Endocarditis
CP of Infective Endocarditis
- The effect of endocarditis are produced by
CP of Infective Endocarditis
- Fever
Persistent Fever: The most common symptoms
CP of Infective Endocarditis
- Heart
CP of Infective Endocarditis
- Lung
Septic pulmonary embolism
CP of Infective Endocarditis
- Spleen
- Splenomegaly
- Splenic artery embolism (infarction)
CP of Infective Endocarditis
- Kidney
- hematuria
- renal failure
- Immune complex glomerulonephritis
CP of Infective Endocarditis
- Neurological
CP of Infective Endocarditis
- Eye
CP of Infective Endocarditis
- Skin
CP of Infective Endocarditis
- Others
- Anorexia
- weight-loss
- malaise
- night sweats
Osler’s Nodules
Janeway Lesions
Splinter Hemorrhage
Other Skin Lesions in Infective Endocarditis
INVx for Infectice Endocarditis
INVx for Infectice Endocarditis
- Blood Culture
INVx for Infectice Endocarditis
- CBC,ESR,CRP
….
INVx for Infectice Endocarditis
- KFTS
Elevated creatinine, Urine analysis: proteinuria & hematuria
INVx for Infectice Endocarditis
- ECG
….
INVx for Infectice Endocarditis
- Chest X-Ray
CHF, pleural effusion, pulmonary embolism
INVx for Infectice Endocarditis
- ECHO
Criteria from peds
Prophylaxis Against IE
Prophylaxis Against IE
- Indications
Prophylaxis Against IE
- Situations
Prophylaxis Against IE
- Drugs
TTT of IE
TTT of IE
- Route
- Dose
- Duration
- Choice
TTT of IE
- Antibiotic regimens for inilial empirical treatment
TTT of IE
- Indication for surgery
Heparin & other anticoagulants are contraindicated in IF for fear of rupture of mycotic aneurysm
…..