L6 blood supply to the CNS Flashcards

1
Q

(recap) Through what **artery branch **does the subclavian artery supply the CNS?

A
  • vertebral artery
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2
Q

what are the** 2 systems of blood supply **to the brain?

A

1.** Carotid -** internal carotid artery & its branches (anterior circulation)
2. Vertebrobasilar - vertibral and basilar branches (posterior circulation)

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3
Q

what do the internal carotid arteries and their branches supply?

A
  • they supply blood to the majority of the forebrain
  • this is why they are classified as the** anterior circulation**
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4
Q

where do the vertebral arteries supply blood to?

A
  • supply blood to the spinal chord
  • brainstem
  • cerebellum
  • posterior cerebral hemispheres (ie occipital and temporal lobes)
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5
Q

what is the circle of willis?

A
  • an anatomical structure that provides an anastomotic **connection between the anterior and posterior circulations **
  • a circle around the hypothalamus and optic nerve at the base of the brain
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6
Q

Briefly describe the anterior circulation

ie describe the branches of the ICA

A

Internal carotid artery branches
* **middle and anterior cerebral artery **- supply the cortex and penetrate the brain to supply deep structures
* ophthalamic artery
* anterior choroidal artery
* posterior communicating artery

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7
Q

Briefly describe posterior circulation
ie the branches of the vertebasilar system

A

vertebrobasilar artery and branches
* vertebral artery
* posterior inferior cerebellar artery (PICA)
* anterior inferior cerebellar artery (AICA)
* Basilar artery
* pontine branches
* superior cerebellar artery
* posterior cerebellar artery

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8
Q

what are the 3 arteries that run along the spinal chord? (longitudinal vessels)

A
  1. anterior spinal artery
  2. right posterior spinal artery
  3. left posterior spinal artery
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9
Q

what are the arteries that supply **each segment **of the spinal cord called?

A

segmental arteries

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10
Q

what do the segmental vessels split into?

A

the anterior and posterior **radicular branches **

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11
Q

what are the** roles/ function** of the anterior and posterior radicular branches?

A
  • they run into cord along dorsal and ventral nerve roots
  • supply lumbar & sacral regions of spinal cord
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12
Q

what are the 2 types of cerebral veins?

A
  1. superficial
  2. deep
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13
Q

what is the function of the superficial cerebral vein?

A
  • drains cortex
  • empties blood into adjacent sinuses of dura
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14
Q

what is the function of the deep cerebral veins?

A
  • they drain the deeper structures - the basal nuclei, internal capsule (white matter structure in brain) & choroid plexus
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15
Q

what are the dural venous sinuses?

A
  • they are major vascular channels contained between the meningeal & periosteal layers of the dura mater
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16
Q

where are most of the dural venous sinuses located next to?

A

the falx cerebri (fold in dura mater) & tentorium cerebelli (extension of dura mater)

17
Q

what are the major dural venous sinuses?

A
  • superior saggital sinus
  • inferior saggital sinus
  • straight sinus
  • transverse sinus
  • sigmoid sinus
18
Q

what is the main function of the dural venous sinuses?

A
  • to drain all venous blood within the cranial cavity into the internal jugular vein
  • they also drain CSF through arachnoid granulations
19
Q

Describe the superior saggital sinus

A
  • **occupies **the longitudinal fissure of the brain (line through both hemipsheres)
  • lies along the superior margin of the falx cerebri
20
Q

Describe the inferior saggital sinus

A
  • lies along inferior margin of falx cerebri
  • joins the great cerebral vein
21
Q

Describe the** straight sinus**

A
  • midline structure
  • located at the** posterior end of the falx cerebri** and the middle of the tentorium cerebelli
22
Q

what is the confluence of sinuses?

A
  • the point of union between the superior saggital sinus, straight sinus, occipital sinus and transverse sinuses
23
Q

describe the transverse sinus

A
  • **begins **at the confluence of sinuses
  • extends along the edges of the tentorium cerebelli
  • **paired **sinus - right and left
24
Q

Describe the sigmoid sinus

A
  • **continuation **of straight sinus
  • paired sinus
  • S shaped sinuses
  • joins the internal jugular vein
25
What is the pathway for the **flow of deoxygenated blood** through the **sinuses**?
*** superior saggital sinus** drains into **confluence of sinus** *** inferior saggital sinus** drains into **straight sinus** which then drains into COS (again) * **confluence of sinus **drains into the **transferse sinus** * **cavernous sinus **drains into the** superior petrosal sinus** which drains into the transverse sinus * transverse sinus drains into **sigmoid sinus** * sigmoid sinus drains into internal jugular vein
26
what are the **channels** called that **connect the lateral ventricles to the 3rd ventricle**?
* intraventricular foramen
27
what **connects** the** 3rd and 4th ventricle**?
* the cerebral aqueduct
28
where are the 4 ventricles located?
* two lateral (left and right) * third ventricle (centre of brain) * 4th (under the cerebellum)
29
recap - Describe CSF circulation
1. CSF drains from the **lateral ventricle** 2. goes to the **3rd ventricle **(through the interventricular foramen) 3. goes from th**e 3rd ventricle to the 4th ventricle** (through the cerebral aqueduct) 4. CSF drains into the **subarachnoid space** and enters the superior saggital sinus through arachnoid granulations 5. from the superior saggital sinus**, the CSF drains into the venous circulation**
30
where are the arachnoid granulations located?
* subdural space - between the arachnoid & dura mater
31
what is an important function of the arachnoid granulations?
* the CSF leaves the subarachnoid space and enters the venous system * granulations allow for** CSF absorption**
32
what is the** blood brain barrier**?
* a physical barrier * formed by tight junctions between endothelial cells
33
what is the** function** of the blood brain barrier?
* prevents harmful substances from passing through * allows substances eg H20, CO2, O2 in * drug delivery
34
what is a stroke and what are the 2 types?
* stroke - inadequate blood flow - oxygen deprivation * two types - ischemic and haemorrhagic stroke
35
Compare the cause of an ischaemic stroke vs haemorrhage stroke
* an ischaemic stroke is caused by blockage or cut off of blood supply to the brain - most common * haemorrhage - bleeding in or around the brain
36
what is a subarachnoid haemorrhage?
* bleeding within the subarachnoid space * major head trauma
37
What is the middle meningeal artery? | branches, function etc
* the middle meningeal artery is a branch of the maxillay artery (ECA) * functions to supply blood to the skull and dura matter of the brain