Key Concepts

Question 1

a decrease in pH in the muscle inhibits which enzyme

Answer 1

PFK

Question 2

What is hexokinase inhibited by in the muscle

Answer 2

Glucose 6-P

Question 3

What is pyruvate kinase inhibited and activated by in muscle

Answer 3

inhibited by ATP and activated by fructose 1,6-BP

Question 4

What is PFK in the liver inhibited and activated by

Answer 4

Inhibited by citrate and activated by fructose 2,3-BP

Question 5

increase in fructose 2,6-BP favours which pathway (glycolysis/gluconeogenesis)

Answer 5

Glycolysis

Question 6

Increase in acetyl CoA favours which pathway (glycolysis or gluconeogenesis)

Answer 6

gluconeogenesis

Question 7

Where is the PPP located

Answer 7

Cytosol of tissues

Question 8

What is glucose activated by

Answer 8

Glycogen 6-P

Question 9

What inhibits and activates phosphorylase B in the muscle

Answer 9

Inhibited by ATP and activated by AMP

Question 10

What inhibits glycogen phosphorylase in the liver

Answer 10

Glucose

Question 11

Increase in Malonyl CoA causes a ( ) in B-oxidation

Answer 11

decrease

Question 12

What are the 2 regulatory reactions in the CAC

Answer 12

Isocitrate -> a-ketoglutarate

a-ketoglutarate -> succinyl CoA

Question 13

What is isocitrate inhibited and activated by

Answer 13

Inhibited by ATP and NADH

Activated by ADP

Question 14

An increase in ADP activates which 2 enzymes

Answer 14

Pyruvate dehydrogenase & isocitrate dehydrogenase

Question 15

A need for ATP = ( ) ADP

Answer 15

Increased