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nevrologia > kefalaio 28-skp (meros 4) > Flashcards

kefalaio 28-skp (meros 4) Flashcards

1
Q

okseia optiki nevritida

A

moni tis ,i meros mias poliestiakis apomielinwtikis pathisis p.x skp i okseia diasparti egkefalomielitida

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2
Q

antidrasi marcus gunn

A

meta apo enalaks fotismo gia elegxo fotokinitikou antanaklastikou stin pasxousa plevrra exoume dievrinsi koris

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3
Q

simeio lhermitte (se auxaniki prosvoli)(stin ateli okseia egkarsia mielitida)

A

paraisthitikou tipou aisthima ilektrikis ekkenwsis pros ti raxi to katw o kai to anw akra kata tin kampsi tis kefalis

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4
Q

i okseia diasparti egkefalomielitida (monofasiki poliestiaki)

A

meta apo loimwksi i emvolio (ara meta apo emfanisi eksanthimatos)

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5
Q

epidimiologia skp

A

g;a 2;1 ,triti dekaetia zois (15-50)(oikogeneis periptwseis 5%)

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6
Q

diataraxes skp

A

kiriws diskiliotita ,seksoualikes diataraxes,epitaktiki ourisi ,miokimies

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7
Q

skp simeio uhthoff

A

otan avksanete i thermokrasia tou swmatos ,epiteinete nevrologiko provlima px tholwsi wrasis

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8
Q

ekswgeneis paragontes pou simvaloun stin eklisi twn ipotropwn

A

loimwkseis, sinaisthimatikes kataponiseis ,travmatismoi, emvoliamsoi ,avksisi thermokrasias somatos ,kiisi

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9
Q

skp mri lipsi estiwn apo gandolinium

A

simainei oti i estia flegmenei ,stamata o aef ,epomenos i estia einai prosfata energopoiimeni

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10
Q

se skp exoume avksisi ti sto eni

A

ig prwtistos g(oligoklonikes zones igg) alla kai a m anososfairinwn ,

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11
Q

parallages skp

A

iportropiazousa optiki nevritida, optiki neyromielitida (devic), kakoithis morfi (okseia) Marbug

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12
Q

poia farmaka mporoun na kanoun taftoxrona : antiflegmonodi ,apoidimatiki anosokatastaltiki drasi , na avksisoun tin agwgimotita twn nevrwn ,aisthima euaiksias ,apokathistoun ton diarragenta aef

A

ta kortikoeidi(methilprednizoloni-se okseia fasi skp)

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13
Q

anepithimites energeies kortikoeidwn

A

aipnia ,evforia, gastrika enoxlimata ,iperglikaimia ,kardiaki arrithmia

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14
Q

azatheioprini gia antimetwpisi skp se poious antendeiknete

A

astheneis me xronia ipatopatheia(avksanei ta ipatika enzima kai kanei endoipatiki xolostasi) ,xronies loimwkseis(anosokatastoli) kai egkimosini

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15
Q

anosokatastaltikes anosothrpopoiitikes therapeies gia skp

A

azathioprine, cyclophosphamide,cyclosporine,methotrexate(gia xronia aftoanosa),interferones(inf-b)betaferon-avomex,copolymer (copaxone ) , mitoxantrone(novantrone-kitarostatiko)

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16
Q

sinoda sklirinsis kata plakas

A

spastikotita,tromos energeias kai ataksia,diplopia ,sfiktiriakes diataraxes,disarthria,disfagia,leitourgia tou enterou(diskiliotita),katathlipsi kai seksoualiki zoi,diapiriniki ofthalmopligia , nevralgia tridimou

17
Q

adrenolefkodistrofia (adl)

A

klironimeitai sta agoria,floioepinefridiaki aneparkeia kai prosvoli kentrikou nevrikou(spastiki tetraparesi kai ekptwsi noitiki) ,diagnwsi kaliergei inovlastwn vriskoume avksimena lipara oksea

18
Q

poia nosos anaptisete logo diataraxis metavolismou sfiggolipidiwn logo eleipsis enzumou aril soulfatasi A

A

metaxrwmatiki lefkodistrofia

19
Q

lefkodistrofies

A

provlima stin sinthesi mielinis(ek genetis) epomenos exoume spastikotita,ataksia kai noitiki kathisterisi

20
Q

usefulness of FLAIR sequences(mri- t2 xwris nero)

A

nekrosi,skp,iparaxnoeidi aimoragia,gia mikres vlaves ipofloiwdeis

21
Q

poia flegmonwdi kittara simmetexoun stin katastrofi tis mielinis

A

Συμμετεχουν Τ- λεμφοκυτταρα,Β-λεμφοκυτταρα,αντισωματα, μακροφαγα

22
Q

mri kai skp

A

t2 vlaves: ipofloiodws(katheti diataksi) ,perikoiliaka(dawson fingers) stelexos, paregkefalida ,nwtiaios mielos , i t1 me gandolinum

23
Q

therapeies skp

A

plasmaferesi kittarostatika

24
Q

klinika simeia skp

A

opisthovolviki nevritis,diplipia,diapiriniki ofthalmopligia,nistagmos,ataksia,piramidiki sindromi,ipaisthisia

25
Q

ms therapies

A

mitoxanthrone-kitarostatiko , natalizumamb-kata tis metanastavsis ,anosotropopoiitiko (inf b,Glatiramer acetate)

26
Q

ti kanei i FTY 720

A

traps t-cell in lymph nodes

27
Q

GILENYA(prepei na exei antiswmata kata vzv)

A

φινγκολιμόδη (fingolimod) είναι τροποποιητής των υποδοχέων της 1-φωσφορικής σφιγγοσίνη(enwnete stous sip twn lemfokitarwn),στα λεμφοκύτταρα, η φωσφορική φινγκολιμόδη αναστέλλει την ικανότητα των λεμφοκυττάρων να εξέρχονται από τους λεμφαδενες

28
Q

therapeia prwtis grammis skp

A

interferon beta, Glatiramer acetate ,terifluomide ,fumaric [DMF

29
Q

therapeia defteris grammis skp

A

Natalizumab ,Fingolimod(gylenya)

•Alemtuzumab ,Cytostatics ,Rituximab(kata b lemfokitarwn)

30
Q

bioximika evrimata optikis nevromielitidas

A

anti nmo igG (anti aqp4 antiswmata)

31
Q

therapeia okseias fasis nmo(optiki nevromielitida)

A

e/f steroeidi,plasmaferesi,retiximab(b lemfokitara)cytarostatika

32
Q

xronia fasi nmo

A

azathioprine,mycofenolate,retuximab

nevrologia (21 decks)

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