kefalaio 28-skp (meros 4)

Question 1

okseia optiki nevritida

Answer 1

moni tis ,i meros mias poliestiakis apomielinwtikis pathisis p.x skp i okseia diasparti egkefalomielitida

Question 2

antidrasi marcus gunn

Answer 2

meta apo enalaks fotismo gia elegxo fotokinitikou antanaklastikou stin pasxousa plevrra exoume dievrinsi koris

Question 3

simeio lhermitte (se auxaniki prosvoli)(stin ateli okseia egkarsia mielitida)

Answer 3

paraisthitikou tipou aisthima ilektrikis ekkenwsis pros ti raxi to katw o kai to anw akra kata tin kampsi tis kefalis

Question 4

i okseia diasparti egkefalomielitida (monofasiki poliestiaki)

Answer 4

meta apo loimwksi i emvolio (ara meta apo emfanisi eksanthimatos)

Question 5

epidimiologia skp

Answer 5

g;a 2;1 ,triti dekaetia zois (15-50)(oikogeneis periptwseis 5%)

Question 6

diataraxes skp

Answer 6

kiriws diskiliotita ,seksoualikes diataraxes,epitaktiki ourisi ,miokimies

Question 7

skp simeio uhthoff

Answer 7

otan avksanete i thermokrasia tou swmatos ,epiteinete nevrologiko provlima px tholwsi wrasis

Question 8

ekswgeneis paragontes pou simvaloun stin eklisi twn ipotropwn

Answer 8

loimwkseis, sinaisthimatikes kataponiseis ,travmatismoi, emvoliamsoi ,avksisi thermokrasias somatos ,kiisi

Question 9

skp mri lipsi estiwn apo gandolinium

Answer 9

simainei oti i estia flegmenei ,stamata o aef ,epomenos i estia einai prosfata energopoiimeni

Question 10

se skp exoume avksisi ti sto eni

Answer 10

ig prwtistos g(oligoklonikes zones igg) alla kai a m anososfairinwn ,

Question 11

parallages skp

Answer 11

iportropiazousa optiki nevritida, optiki neyromielitida (devic), kakoithis morfi (okseia) Marbug

Question 12

poia farmaka mporoun na kanoun taftoxrona : antiflegmonodi ,apoidimatiki anosokatastaltiki drasi , na avksisoun tin agwgimotita twn nevrwn ,aisthima euaiksias ,apokathistoun ton diarragenta aef

Answer 12

ta kortikoeidi(methilprednizoloni-se okseia fasi skp)

Question 13

anepithimites energeies kortikoeidwn

Answer 13

aipnia ,evforia, gastrika enoxlimata ,iperglikaimia ,kardiaki arrithmia

Question 14

azatheioprini gia antimetwpisi skp se poious antendeiknete

Answer 14

astheneis me xronia ipatopatheia(avksanei ta ipatika enzima kai kanei endoipatiki xolostasi) ,xronies loimwkseis(anosokatastoli) kai egkimosini

Question 15

anosokatastaltikes anosothrpopoiitikes therapeies gia skp

Answer 15

azathioprine, cyclophosphamide,cyclosporine,methotrexate(gia xronia aftoanosa),interferones(inf-b)betaferon-avomex,copolymer (copaxone ) , mitoxantrone(novantrone-kitarostatiko)

Question 16

sinoda sklirinsis kata plakas

Answer 16

spastikotita,tromos energeias kai ataksia,diplopia ,sfiktiriakes diataraxes,disarthria,disfagia,leitourgia tou enterou(diskiliotita),katathlipsi kai seksoualiki zoi,diapiriniki ofthalmopligia , nevralgia tridimou

Question 17

adrenolefkodistrofia (adl)

Answer 17

klironimeitai sta agoria,floioepinefridiaki aneparkeia kai prosvoli kentrikou nevrikou(spastiki tetraparesi kai ekptwsi noitiki) ,diagnwsi kaliergei inovlastwn vriskoume avksimena lipara oksea

Question 18

poia nosos anaptisete logo diataraxis metavolismou sfiggolipidiwn logo eleipsis enzumou aril soulfatasi A

Answer 18

metaxrwmatiki lefkodistrofia

Question 19

lefkodistrofies

Answer 19

provlima stin sinthesi mielinis(ek genetis) epomenos exoume spastikotita,ataksia kai noitiki kathisterisi

Question 20

usefulness of FLAIR sequences(mri- t2 xwris nero)

Answer 20

nekrosi,skp,iparaxnoeidi aimoragia,gia mikres vlaves ipofloiwdeis

Question 21

poia flegmonwdi kittara simmetexoun stin katastrofi tis mielinis

Answer 21

Συμμετεχουν Τ- λεμφοκυτταρα,Β-λεμφοκυτταρα,αντισωματα, μακροφαγα

Question 22

mri kai skp

Answer 22

t2 vlaves: ipofloiodws(katheti diataksi) ,perikoiliaka(dawson fingers) stelexos, paregkefalida ,nwtiaios mielos , i t1 me gandolinum

Question 23

therapeies skp

Answer 23

plasmaferesi kittarostatika

Question 24

klinika simeia skp

Answer 24

opisthovolviki nevritis,diplipia,diapiriniki ofthalmopligia,nistagmos,ataksia,piramidiki sindromi,ipaisthisia

Question 25

ms therapies

Answer 25

mitoxanthrone-kitarostatiko , natalizumamb-kata tis metanastavsis ,anosotropopoiitiko (inf b,Glatiramer acetate)

Question 26

ti kanei i FTY 720

Answer 26

traps t-cell in lymph nodes

Question 27

GILENYA(prepei na exei antiswmata kata vzv)

Answer 27

φινγκολιμόδη (fingolimod) είναι τροποποιητής των υποδοχέων της 1-φωσφορικής σφιγγοσίνη(enwnete stous sip twn lemfokitarwn),στα λεμφοκύτταρα, η φωσφορική φινγκολιμόδη αναστέλλει την ικανότητα των λεμφοκυττάρων να εξέρχονται από τους λεμφαδενες

Question 28

therapeia prwtis grammis skp

Answer 28

interferon beta, Glatiramer acetate ,terifluomide ,fumaric [DMF

Question 29

therapeia defteris grammis skp

Answer 29

Natalizumab ,Fingolimod(gylenya)

•Alemtuzumab ,Cytostatics ,Rituximab(kata b lemfokitarwn)

Question 30

bioximika evrimata optikis nevromielitidas

Answer 30

anti nmo igG (anti aqp4 antiswmata)

Question 31

therapeia okseias fasis nmo(optiki nevromielitida)

Answer 31

e/f steroeidi,plasmaferesi,retiximab(b lemfokitara)cytarostatika

Question 32

xronia fasi nmo

Answer 32

azathioprine,mycofenolate,retuximab