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nevrologia > kef 25 eksopiranidika > Flashcards

kef 25 eksopiranidika Flashcards

1
Q

leitourgeies eksopiramidikou sistimatos

A

elegxei kinitikotita (mazi me piramidiko kai paregkefalida),dimiourgia aftomatikwn kinisewn(kataposi) ,avtomatopoiimenwn kinisewn(grafi kai vadisi),miikos tonos,rithmisi ekousias kinitikotitas

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2
Q

anatomikoi sximatismoi eksopiramidikou

A

prokinitikos floios,vasika gagglia(k+f),ipothalamios pirinas tou luys,melena ousia kai o erithros pirinas

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3
Q

melenoravdoti(melena ousia -kefkoforo kai kelifos fak) sindesi meros tou eksopiramidikou poios o nevrodiavivastis

A

ntopamini(apo ntopaminergikous nevrwnes melenas ousias)

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4
Q

nosoi eksopiramidikou pws ekdilwnountai

A

diataraxes kinitikotitas(akinitika diskamptika sindroma parkinson-iperkinitika sindroma-akousies kiniseis: tromos distonia xoreia valismos mioklonos nosos tou wilson )

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5
Q

kliniki ekdilwsi parkinson

A

TROMOS IREMIAS pou ipoxorei se ekousies kiniseis kai ipno kai kefali kai katw gnathos, DISKAMPSIA logo ipertonias miwn(odontotos -molivdosolinas -kirti thesi somatos) kai VRADIKINISIA (dinoume amantadini)eidika stin enarksi,ipomimia (anekfrasto prosopo) meiwsi aftomatikwn kai aftomatwn leitourgeiwn =>sieloreia ,mikra siromena vimata,mikrografia,argi vadisi xwris aiwrisi twn akrwn,diataraxes osfrisis DIATARAXES ANS, PSIXIKI SFAIRA (katathlipsi diataraxi ipnou) ,diataraxi ANTANAKLASTIKOU STASEWS

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6
Q

oikogenis parkinson

A

gonidio sto xromosoma 4(epikratitiki metavivasi prwimi enarksi)

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7
Q

ntopamini

A

sintithete sta vasika gagglia apo tirosini,metatrepete se l dopa kai meta ntopamini ,metavolizete apo tin compt kai tin monoaminoksidasi b

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8
Q

se parkinson exoume pathan

A

somatia lewy(iosinofila kittaroplasmatika egkeista se nevrwnes pou den exoun ekfilistei) kai ekfilisi basikwn gagkliwn(ntopaminergikwn nevrwnwn)

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9
Q

pote ekdilwnete i parkinson

A

otan katastrafei to 80% tis melenas

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10
Q

ptwto simptwma parkinson

A

diskolia na sikwthoun apo xamili karekla (diataraxes antanaklastikwn stasews)—anosmia kai ipnous rem,viwnoun ton ipno tous

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11
Q

therapeia parkinson

A

l dopa(proima:kanei naftia emeto orth ipotasi) kai anastolea tou enzimou apokarvoksilasi

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12
Q

opsimes parenergeies farmakwn gia parkinson(ntopaminergikwn)

A

iperkinisies (distonia kai xorioatherwsi) sigxisi psevdaisthiseis kai psixosikomorfes ekdilwseis,ipertonia(on off)

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13
Q

antagwnistes ntopaminis

A

bromokriptini pergolidi prampeksoli ropiniroli

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14
Q

entakaponi—-selegilini

A

anastoleas compt=——anastoleas mao

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15
Q

farmaka pou kanoun parkinsonismo

A

nevroliptika(gia psixwseis),antiemetika kai gia therapeia iligkou afta kanoun vradikinisia-akathisia

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16
Q

pws antimetwpizete o farmakevtikos parkinsonismos

A

antixolinergikes ousies (antixolinergikes xrisimopoioumai kai sto parkinson tromo seiloreia)

17
Q

nosos somatiwn lewy(alpha-synuclein and ubiquitin in neurons ston floio kai vasika gagglia)

A

eksopiramidiki simptwmatologia(akinitikou-diskamptikou tipou, diataraxi isoropias kai ptwseis) ,sinaisthimatiki astatheia (psevdaisthiseis paralirimatikes ides) kai anoia(noitiki ekptwsi)

18
Q

iperkinitika sindroma (akousies kiniseis logo eksopiramidikis atiologias)

A

akousies kiniseis ,tromos ,distonia, xoreia ,vallismos ,stereotipes kiniseis(tik ) mioklonos, nosos wilson

19
Q

vlavi eksopiramidikou -iperkinisies-xoreia huntington

A

genetikos avksimenos arithmos cag ,kodikopoioun tiin prwteini xantigktini,emfanizei proodevtiki ekptwsi noitikwn leitourgiwn ,psixikes diataraxes kai xoreiomorfes iperkinisies

20
Q

vlavi se ipothalamio somatio tou luys

A

kanei vallismo (viaies kiniseis megalou evrous)

21
Q

nosos wilson ipatofakoeidiki ekfilisi

A

ekfilisi kittarwn ipatos kai fakoeidous,diataraxi metavolismou tou xalkou,den apovalete mesw xolis … therapeia D penikilamini

22
Q

nevroakathokittwsi

A

stomatoprosopikes iperkinisies distonikou tipou ,ekselisontai se xoreia kai noithiki ekptwsi

23
Q

akinitika -dispamptika sindroma ekopiramidikis sindromis

A

parkinson,farmakevtiko parkinson,floiobasiki ekfilisi,nosos somatiwn lewy,metegkefalidikos parkinsonismos,proodeftiki iperpiriniki paralisi,polisistimatiki atrofia

24
Q

aitiopathogeneia parkinson

A

den einai gnwsti ,pithanon drasi ekswgwgenwn(ioi toksikoi->mptp se toksikomaneis kai perivalintikoi paragontes) klironimikotita…..>

25
Q

diagnwstika sfalmata gia nosou parkinson

A

diskampsia kai vradikinisia den einai logo piramidikis aitiologias,tromos einai eksopiramidikos kai oxi idiopathis,oi aisthitikes diataraxes einai ipokeimenikes tou parkinson kai oxi mioskeletikou,diataraxi omilias sielreia sto parkinson den einai psevdopromikiki,katathlipsi einai apo parkinson

26
Q

poia sindroma apoteloun ta epavksimena parkinsonika sindroma (dld exoun eksopiramidiki diataraxi kai prosvoli nevrikou sistimatos)

A

proodeftiki iperpiriniki paralisi,polisistimatiki atrofia ,floiovasiki ekfilisi kai nosos swmatiwn lewy,metegkefalitidikos parkinsonismos

27
Q

proodeftiki iperpiriniki paralisi(mesi epiviwsi 8 y den iparxei therapeia)

A

diatarasete i ofthalmokinitikotita(arxika katheti kinisi),ipertonia mies afxena kai omiki zoni ,strofi kefalis panw,sixnes ptwseis ,vradikinisia xwris tromo

28
Q

polisistimatiki atrofia (shy dragger diataraxes ans ,elaiogefiro paregkefalidiki ekfilisi paregkefalidiki diataraxi diskampsia kai vradikinisia,melainoravdwti ekfilisi-amiges eksopiramidiko)

A

diataraxes anapnois ,simeia piramidikis kai paregkefalidikis prosvolis ,diataraxes egkefalikwn sizigiwn,prosvoli prosthiwn keratwn

29
Q

floiovasiki ekfilisi

A

ekfilisi metwpiaiou kai vregmatikou floiou kai vasikwn gaggliwn exoume monoplevri ipertonia vradikinisia apraksia,sindromo ksenou akrou-perierges akousies kiniseis,diataraxi noitikwn leitourgeiwn

30
Q

eidi tromou

A

TROMOS IREMIAS:parkinson kai epavksimena ,TROMOS THESEWS:idiopathis(primidoni barvitouriko) ,endokrinika-iperth ipoglikaimia,farmaka trikiklika antikatathliptika agwnistes ntopaminis theofilini ,periferiki nevropatheia TROMOS TELIKOU SKOPOU: paregkefalidiki diataraxi ,skp,aggeiaki vlavi ,nosos wilson

31
Q

therapeia idiopathous tromou

A

propranoloni pirimidoni

32
Q

distonia (idiopathis,flefarospasmos,stomatotraxilii distonia-sindomo meige,spasmwdiko raivokrano,spasmos grafewn,distonia l dopa ,defteropathis-wilson perigenitikes vlaves)

A

sispaseis miwn poikilis diarkeias kai entasis ,kanoun kiniseis strofikes epanalavanomenes pathologikes theseis melwn swmatos

33
Q

therapeia distoniwn

A

benzeksoli ,allantiki otksini

34
Q

xoreia –athetwsi

A

aifnidies askopes tinagmoeidis kiniseis —ofioeidi poreia

35
Q

revmatiki xoreia sydenham

A

sxetizete me revmatiko pireto se paidia 5-15,ipoxorei me therapeia gia revmatiko pireto

nevrologia (21 decks)

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