Kaplan Videos Flashcards
Spinal tap location
between L3-L4 and L4-L5 because the conus medullaris (end of spinal cord) ends at L2 in adults
Nine layers pierced by lumbar puncture needle
Skin, superficial fascia, deep fascia, supraspinous ligament, interlaminar space, ligamentum flavum, epidural space, dura, (“pop”), ARACHNOID MATER (last tissue pierced), subarachnoid space with CSF
Motor origin
Ventral horn
Sensory Origin
Dorsal horn
Fibers in Dorsal Horn medial division, proprioception
1a, 1b fibers
Fibers in Dorsal Horn medial division, touch
2, A-beta fibers
Fibers in Dorsal Horn lateral division, sharp pain and cold
3, A-delta fibers
Fibers in Dorsal Horn lateral division, dull pain and warmth
4, C fibers
Motoneurons in Ventral Horn and what they innervate
Alpha MN innervate skeletal muscle NMJ.
Delta MN innervate skeletal muscle spindles.
(medial MN’s in ventral horn innervate proximal muscles. lateral MN’s innervate distal muscels).
If UMN CST lesion is between the cerebral cortex and medulla above the pyramidal decussation, where will the spastic paresis be present?
If the lesion is below the medulla, where will the spastic paralysis be present?
If the lesion is a LMN lesion, where will the deficit be?
Spastic weakness below and CONTRALATERAL to the lesion.
Spastic weakness below and IPSILATERAL to the lesion.
FLACCID weakness ipsilateral to the skeletal muscle their axons innervate.
Sensory system that controls: conscious proprioception, fine touch, vibration, pressure, 2-pt discrimination.
Dorsal column Pathway- Medal Lemniscal System
Sensory system that controls: conscious proprioception, fine touch, vibration, pressure, 2-pt discrimination.
- Lesion: loss of senses __(above/below)__ lesion
- Site of lesion: _(affected/unaffected)__ side of body
- Location of decussation: (lesion above this is CL symptoms; below is ipsilateral symptoms)
Dorsal column Pathway - Medal Lemniscal System
- Lesion: loss of senses __ABOVE__ lesion
- Site of lesion: _AFFECTED__ side of body
- Location of decussation: (lesion above this is CL symptoms; below is ipsilateral symptoms)
How to tell where the lesion of the dorsal column lies: Romberg test.
Decreased balance + eyes OPEN = cerebellar lesion.
Decreased balance + eyes CLOSED = DC-ML lesion (bc vision compensates for interrupted proprioceptive input from DC).
Sensory system that controls: Anesthesia (loss of Pain and Temperature sensation)
Spinothalamic Pathway - Anterolateral System
Sensory system that controls: Anesthesia (loss of Pain and Temperature sensation)
- Lesion: loss of senses __(above/below)__ lesion
- Site of lesion: _(affected/unaffected)__ side of body
- Location of decussation: (lesion above this is CL symptoms; below is ipsilateral symptoms)
- Lesion: loss of senses __1-2 segments BELOW and beyond__ the lesion
- Site of lesion: _AFFECTED__ side of body
- Location of decussation: in the Spinal cord, so always CL symptoms below the lesion. Tract intact rostral to the lesion
Thalamic nucleus that Dorsal column Pathway - Medal Lemniscal System and Spinothalamic Pathway - Anterolateral System.
VPL
Where does Spinothalamic Pathway - Anterolateral System travel?
Neuron 1: travels from receptor to DRG.
Neuron 2: DRG, enters SC, travels 1-2 segments up/down in Lissauer’s tract. Decussates in SC and continues up through Medulla to VPL in thalamus.
Neuron 3: VPL in Thalamus to post central gyrus
What tract mainly carries unconscious proprioceptive input form muscle spindles and GTOs to cerebellum?
Spinocerebellar tract
a) the dorsal spinocerebellar tract
b) the cuneocerebellar tract
the subsets of spinocerebellar tract
a) the dorsal spinocerebellar tract - from lower limb to externeal cuneate nucleus in BS
b) the cuneocerebellar tract - from upper limb to Clarke’s nucleus in SC
both pass through inferior cerebellar peduncle and then end, ipsilateral ascent the entire time
reflex contraction of skeletal muscle - name the two neurons involved in efferent and afferent signals.
1a dorsal root
LMN (aka alpha motor neurons)
UMN have what net effect on muscle stretch reflex?
inhibitory
Dorsal roots for prop/touch
For Pain/temp
Proprioception/touch: 1a, 1b, A-beta
Pain and temp: A-delta and C
Infant with gait ataxia, dysarthria, hand clumsiness, loss of position sense, imparied vibratory sensation, and loss of tendon reflexes.
Friedreich’s ataxia. Frataxin gene, chromosome 9
Bilateral paralysis with suppressed reflexes
Poliomyelitis, Werdnig-Hoffman Disease, ALS, or ASA occlusion?
Poliomyelitis, Werdnig-Hoffman Disease (LMN lesion only; VH)