JVD 2018 #1 - Histopathologic Diagnoses From Biopsies of the Oral Cavity in 403 Dogs and 73 Cats

Question 1

Rank the following lesions in cats from most to least common:

Malignant tumors; inflammatory lesions; odontogenic tumors

Answer 1

• 51% inflammatory
• 47% malignant neoplasm (of which 27/37 are SCC - 37% of total)
• 3% odontogenic

Question 2

Rank the following lesions in dogs from most to least common:

Odontogenic Tumors, malignant neoplasm, inflammatory lesions

Answer 2

• 37% malignant neoplasia
• 34% odontogenic tumors,
• 28% inflammatory,

Question 3

Of the odontogenic lesions diagnosed in dogs, rank the following from most to least frequent:

Odontogenic cyst; CAA; POF;

Answer 3

• POF 18% of biopsies
• CAA 14% of biopsies
• Odontigenic cyst 2% of biopsies

Question 4

What differences were detected between this study and the UC davis data (reported biopsies for 1995-2001) with regards to the prevalence of odontogenic tumors in biopsy samples, and what is the likely origin of the discrepancy?

Answer 4

This study had more odontogenic tumors (34% versus 13%) In the UC Davis data they had a category for hyperplasias, which included POF’s separate from odontogenic tumors.

Note that this is the table from verstraete chapter 39, NOT the Fiani article Clinicopathologic characterization of odontogenic tumors and focal fibrous hyperplasia in dogs: 152 cases (1995–2005) (which is also important)

Question 5

In this study rank the occurrence of the following malignant tumors.

SCC; MM; FSA; OSA

How does this contrast with the UC Davis data?

Answer 5

• This study:

1. SCC 7%
2. FSA 6%
3. MM 4%
4. OSA 4%

• Davis Data

1. MM & SCC 7%
2. FSA 2%
3. OSA 2%

Question 6

what are predisposing factors identified for oral malignant melanoma?

Answer 6

Males, cocker spaniels and heavily pigmented dogs predisposed

Question 7

What is the reported most common intraoral location for a POF, and what breed is predisposed?

Answer 7

Rostral maxilla (47%) - this is from Fiani article, site not reported in Wingo.

Boxer

Question 8

What is the reported most common location for a CAA?

Answer 8

Rostral mandible (41%) - this is from the fiani article, site not reported in Wingo