JVD 2014 # 3 - Apically Repositioned Flap for Gingival Enlargement - VETERINARY DENTISTRY AT WORK Flashcards

1
Q

According to Robert Furman, BVMS, MRCVS, in

Apically Repositioned Flap for Gingival Enlargement - VETERINARY DENTISTRY AT WORK

What is the proposed mechanism for cyclosporine induced gingival hyperplasia?

A

Alterations in calcium influx in gingival tissue, but exact mechanism unknown

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2
Q

According to Robert Furman, BVMS, MRCVS, in

Apically Repositioned Flap for Gingival Enlargement - VETERINARY DENTISTRY AT WORK

How does decreased calcium in gingival tissue result in gingival enlargement?

A

dec. calcium leades to dec. transglutaminase, which is required for normal apoptosis,

imbalance between apoptosis and proliferation results in enlargement

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