JAALAS 2010 No. 5 KD Flashcards
Schuler et al. Measurement of Fetal Biparietal Diameter in Owl Monkeys .What is the genus and species or the owl monkey?
Aotus nancymaae
Which of the following harbor cercopithicine herpesvirus 1?
a. Pan troglodytes
b. Macaca fascicularis
c. Aotus nancymaae
d. Saguinus Oedipus
b. Macaca fascicularis
What is the gestation of the owl monkey?
a. 143-146 days
b. 60-63 days
c. 132-135 days
d. 152-155 days
c. 132-135 days
Arbona et al. Treatment and Eradication of Murine Fur Mites.What is the most common genus/species of fur mite in murine colonies
Myobia musculi and Myoptes musculinus
From what class of drugs does ivermectin belong?
Avermectin
What route(s) can ivermectin be administered
PO, SC, topical
Bennett et al. Multidimensional Cost-Benefit Analysis to Guide Evidence-Based Environmental Enrichment.1. How can bedding promote species specific behavior in NHPs?
Bedding helps promote foraging and provides a natural substrate for animals than bare pens provide. Also, reduces aggression, over grooming, and other abnormal behaviors.
- What are the major cost categories that should be considered when conducting a cost benefit analysis of environmental enrichment programs?
Cost categories should include: labor, materials, supplies and facilities maintenance costs.
Pavek et al. Operation of an Air Filtration Device Results in Morbidity and Mortality in Growing Chickens (Gallus gallus domesticus
Oxidative damage has been found to result from ____________ exposure to sound levels __________ in numerous species.
A. Acute, 45-85dB
B. Chronic , greater than 85dB
C. Chronic, 45-85 dB
D. None of the above
B. Chronic and greater than 85db
The hearing frequency range of chickens is: A. 4-16Hz B. 1-5 kHz C. 1-70kHz D. 0.35-3.15kHz
D. 0.35-3.15 kHz
Macrovibration aversion and physiologic effects have been shown to occur in fully grown chickens. True or False
True
Arbona et al. Treatment and Eradication of Murine Fur Mites.1. Which species of fur mites is reported to preferentially inhabit the forehead and cheeks?
Myobia musculi
- Which species reportedly prefers the ventral abdomen and inguinal areas?
Mycoptes musculinus
- In this study, what percentage of animals tested positive with the pelt examination?
Zero
- True or False: these authors implemented a 3 month post treatment testing moratorium prior to initiating follow up testing.
True
Tavakkol et al. Resident Bacteria Flora in the Skin of C57BL/6 Mice .Which bacterial genus was the most commonly cultured from the mice SPF C57BL/6 used in this study?
a. Staphylococcus
b. Enterococcus
c. Bacillus
d. Streptococcus
a. Staphyococcus
T/F: Culture techniques alone are sufficient for quantifying and identifying the microflora from skin samples.
False
Which of the following Staphylococcus species was not isolated from the mice in this study?
S. epidermis–the comst predominant on human skin.
Reynolds et al. Noise in a Laboratory Animal Facility .How is it that the noise of a jack hammer, which produces noise of a high decibel level, can be heard by humans but not mice?
Jackhammers prodcue noise of a high decible level but a low frequency; this frequency is low enough and out of the range where a mouse cannot accurately hear it.
What is the hearing range of a mouse in frequency?
Ultrasonic, 1-100KHz
What are the OSHA limits for decibel exposure for an employee without hearing protection averaged over an 8 hour work day?
90 Db
What is the limit of decibel exposure over an 8 hour work day that then requires annual testing/training
85 dB
Kanthaswamy et al. Population Genetic Statistics from Rhesus Macaques .List ways in which animal populations lose genetic diversity
Founder effect, intergenerational drift, nonrandom mating, genetic bottlenecks
T/F – Macaques of full-Chinese, full-Indian, or hybrid origin may be used interchangeably in all research studies.
False.Macaques of full-Chinese and full-Indian origins can exhibit profound phenotypic differences in physiologic and behavioral traits that are controlled by genetic mechanisms. Inclusion of macaques from different geographic regions or their hybrids in experimental research may confound interpretation of phenotypic differences due to inflation of the genetic contribution to phenotypic variances.
Adamson et al. Assessment of Carprofen and Buprenorphine on Recovery of Mice .What were the factors used to assess the pain score in the mice, and what postural movement indicative of pain was noted in all post surgical groups?
Hair coat, eyes, coordination and posture and overall condition were assessed in the scoring system. The abdominal stretch, and stretch and walk, were commonly noted in all post surgical groups.
What treatment appeared to have the most negative effect on post operative recovery?
a. Saline
b. Buprenorphine
c. Carprofen
d. Combination of buprenorphine and carprofen
B. Buprenorphine
What important conclusions were made by the researchers regarding pain management in laboratory animals?
Analgesic choice and the level of pain must be considered to help eliminate negative consequences on post operative recovery. Visual assessments of pain should be used carefully as some analgesics may have side effects that elevate the score. There is a need for further exploration of pain management dosing regimens and drugs in laboratory species.
Bourque et al. Comparison of Buprenorphine and Meloxicam for Postsurgical Analgesia in Rats.Which of the following is not an adverse effect reported with use of buprenorphine in rodents?
a. Rebound hyperalgesia
b. Variability in potency between sexes
c. Variability in potency between strains
d. Anorexia and/or pica
e. Renal toxicity
e. Renal toxicity
Which of the following statements is not supported in this study comparing post-operative use of buprenorphine and meloxicam in rats?
a. Meloxicam causes less reduction in body weight than buprenorphine
b. Meloxicam causes less reduction in food consumption than buprenorphine
c. Meloxicam causes less reduction in locomotor activity than buprenorphine
d. Meloxicam has less stimulatory effect on daytime heart rate measurements than buprenorphine
e. Meloxicam has less stimulatory effect on nighttime mean arterial pressure than buprenorphine
d. Melsoxicam has less stimulatory effect on daytime heart rate measurements than buprenorphine.
Roble et al. A Comprehensive Laboratory Animal Facility Pandemic ResponseWhy is cryopreservation recommended in the article?
To mitigate research losses in the event of large scale animal euthanasia
Which of the following is NOT a major consideration when creating a pandemic response plan?
a. Recruitment of essential personnel
b. Food and bedding supplies
c. Animal euthanasia
d. Large scale utility outages
e. Disposal of animal carcasses
Large scale utility outages
T/F. During an influenza outbreak, there is a potential for humans to pass the virus to animals in the research facility.
True
Arbona et al. Treatment and Eradication of Murine Fur Mites.1. True/False Ivermectin administration has been associated with toxicity in some mouse strains and stocks
True
- How long is the life cycle for Myobia musculi and Mycoptes musculinus
Myobia musculi = 23 days
Mycoptes musculinus = 8-14 days
- True/False Chronic ascariasis may provoke secondary amyloidosis due to long-standing dermatitis.
True
Schutt and Turner. Microchip-Associated Sarcoma in a Shrew, What is the genus and species of the house musk shrew?
a. Suncus murinus
b. Mus musculus
c. Rousettus aegyptiacus
d. Octogon degus
e. Acrobates pygmaeus
a. Suncus murinus = shrew
Microchip-associated neoplasms of laboratory animals are generally classified as:
a. Neuroendocrine and malignant
b. Epithelial and benign
c. Neuromuscular and benign
d. Mesenchymal and malignant
e. Round-cell and malignant
Mesenchymal and malignant
Vimentin is an immunohistochemical marker for which type of tissue?
a. Neural
b. Endocrine
c. Mesenchymal
d. Smooth muscle
e. Adipose
c. Mesenchymal
Hamir and Rupprecht. Pulmonary Idiopathic Alveolar Ossification in a Raccoon .Name the genus and species of the common raccoon
Procyon lotor
What is a common histochemical stain for amyloid?
Congo Red
What modified histochemical stain was used in this study to identify intracytoplasmic and intranuclear lead inclusions?
Ziehl-Neelsen
Asfaw and Sun. Presumed Mycobacteriosis in Laboratory Zebra Finch .1. Which form of presumed mycobacteriosis was found in the duodenum of the Zebra finch?
Atypical form
- Which of the following is the scientific name of the Zebra finch?
a. Spinus cucullatus
b. Carduelis carduelis
c. Taeniopygia guttata
C. Taeniopygia guttata
- Which stain was used to identify the organisms presumed to be Mycobacterium spp?
Acid-Fast (Ziehl-Neelsen)
Daviau and Merton. Nonsurgical Repair of a Pseudoaneurysm in a Cynomolgus Macaque .1. Pseudoaneurysm and formation of AV fistulas are common complications of femoral blood draws in NHP. T/F
False. These are rare.
- What feature can be palpated to differentiate between a hematoma and pseudoaneurysm?
Hematomas are static whereas a trill can be palpated in a pseudoaneurysm as the blood flows with the cardiac cycle.
- UGCR requires: a) an ultrasound probe b) a stent c) surgical access of the pseudoaneurysm d) Doppler verification of the absence of an AV fistula
a. ultrasound probe.
