iontophoresis Flashcards
iontophoresis
current flow between electrodes push ions through skin
i.e drug
T/F iontophoresis is direct
true
postive ions flow to the __
cathode (neg)
negative ions flow to the __
anode (pos)
T/f current flows in both direction in tissue
true
can drugs have voltage
yes a pos drug can drift towards neg electrode etc..
three was passages across skin happen
electomigration
electroporation
electroosmosis
electromigration
sweat ducts
hair follicles
electroporation
mechanism unknown but skin porosity is increased by estim
electroosmosis
bulk movement creates a stream
iontophoresis applications
4% acid
2 ma DC
20 mins
5 times in 2 wks
outcome measures iontophoresis
pain scale
LEFS
ADLs
iontophoretic equation
dosage = current x mins
amount of drug delivered is proportional to:
current density, and time of application
how much push and how long the push is
T/f ions is proportional to cube root of current density x time of application
tr