inflammation Flashcards

1
Q

5 cardinal signs of inflammation

A

Heat
Redness
Swelling

Pain
Loss of Function

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2
Q

goal of minimizing inflammation

A

minimize collateral damage

stop inflammatory process, down regulate inflammatory signal and get back to normal

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3
Q

why get rid of heat

A

increases cellular activity

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4
Q

why get rid of redness

A

its been theres vasodilation (increase in blood flow)

hyperaemia

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5
Q

why get rid of pain

A

its from pressure of swelling (mechanical) and chemical irrational of nerve

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6
Q

why get rid of swelling

A

swelling means increased osmotic pressure

and hydrostatic pressure in vessel

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7
Q

osmotic pressure is pulling or pushing

A

pulling

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8
Q

osmotic pressure

A

pulling

pressure to prevent flow of water across membrane via osmosis

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9
Q

hydrostatic

A

pushing
pressure on the walls

by systolic force

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10
Q

what mediates vasodilation

A

histamine

serotonin

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11
Q

what mediates increased vascular permeability

A

bradykinin
histamine
serotonin

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12
Q

what mediates chemotaxis

A

histamine
a bunch of kines

mono, kalli, lympho kines

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13
Q

what mediates fever response

A

prostaglandiins

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14
Q

what mediates pain

A

bradykinin
prostaglandins
hageman factor

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15
Q

if theres a vascular response, what changes in the area

A

vasodilation then constriction

slowing blood flood

accumulation of interstitial fluid

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16
Q

if theres a hemostatic response, what changes in the area

A

retraction / sealing off blood vessels

formation of platelet clots

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17
Q

if theres a cellular response, what changes in the area

A

leukocytes move to the area

18
Q

if theres an immune response, what changes in the area

A

activation of complement system

19
Q

purpose of ice

A

strong evidence it helps with pain

decrease metabolism of good cells, decrease secondary cell damage

20
Q

T/F strong evidence ice helps with secondary cell death

A

moderate

21
Q

purpose of rest

A

minimize further injury

22
Q

purpose of compression

A

increase pressure in tissue

counteract hydrostatic pressure

23
Q

purpose of elevation

A

reduce hydrostatic pressure in vessel

24
Q

whats Peace and Love

A

Protect elevate avoid inflammations, modalities, compress, education

optimal loading, vascularization, exercise

25
Q

is ice machine better than ice

A

same

26
Q

goal of managing edema

A

reduce viscosity

thin out the snot

27
Q

how to manage edema

A

soft tissue massage
electric
mm pumping
compression

28
Q

how to manage swelling

A

facilitate resorption of fluid

soft tissue massage
mm pump
elect
lympth draining
compression
29
Q

is normal intra articular pressure positive or negative

A

slightly negative

30
Q

if injured, intraarticular pressure becomes

A

more positive

31
Q

fluid moves in and out of joint through

A
synovial membrane (with movement)
cartilage / bone interface
32
Q

How to reduce intra articular pressure

A

joint movement

change joint pression (traction, compression)

33
Q

Outcome measures to know if you’re doing good

A

VAS
circumferential measures
LEFS

MDC MCID

34
Q

whats MDC

A

minimal detectable change

35
Q

whats MCID

A

minimal clinically important difference

36
Q

VAS

MCID

A

13mm for initial less than 34

28mm for initial score more than 67

37
Q

what circumferential measure if MDC

A

> 0.5 cm

38
Q

MDC in edema swelling volume

A

150ml

39
Q

LEFS

MDC
MCID

A

9

9

40
Q

DASH
MDC
MCID

A

8-17

10.2