Introduction to Toxicology and General Principles of Drug Interaction

Question 1

Risk is a product of what?

Answer 1

Toxicity

Exposure

Question 2

True or false, drug interactions usually occur in vivo?

Answer 2

False

Question 3

The destruction of cell maintencance involves what?

Answer 3

Destruction of ATP synthesis

Question 4

Oxidative stress is an example of which mechanism of toxic action?

Answer 4

Impairment of internal maintenance

Question 5

Actions of endocrine disrupting substances are classified as?

Answer 5

Dysregulation of gene expression

Question 6

The stage of disrepair includes the following except: apoptosis, necrosis, fibrosis and cancer?

Answer 6

Apoptosis

Question 7

This kind of exposure is the most effective for the toxicant to enter the body?

Answer 7

Intravenous

Inhalation

Question 8

In entrohepatic recirculation, the drug is converted back into this form?

Answer 8

Lipophilic

Question 9

The study of toxicokinetics can be used to predict the following?

Answer 9

Plasma drug concentration

Amount of drug absorbed

Predicted time for substance to reach different compartments

Question 10

True or false, drug interactions can occur in vitro and in vivo?

Answer 10

True

Question 11

Pharmacologic-pharmacodynamic drug interaction involves?

Answer 11

Agonist-antagonist interaction