Adverse Drug Reaction Flashcards

1
Q

Which immunologically related adverse drug reaction takes 1 to 3 weeks to manifest?

A

Type III

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2
Q

Which drugs cause drug induced vasculitis?

A

Allopurinol

Carbamazepine

Cephalosporins

Ciprofloxacin

Clathromycin

Hydralazine

Naproxen

Propylthiourracil

Terbutaline

Vitamins

Warfarin

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3
Q

What is the dermal manifestation of adverse drug reaction to thiol drugs like enalapril, cephalosporins and piroxicam?

A

Pemphigus

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4
Q

What is the risk factor shared by both immune and non-immune reactions?

A

Systemic lupus erythematosus

HIV infection

Female gender

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5
Q

Tinnitus is an unpredictable intolerance to small doses of what?

A

Aspirin

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6
Q

Which of the following cannot be desentisized: peripheral neuropathy from rifampicin, rash from isoniazid, Steven-Johnson syndrome and morbiliform rash?

A

Steven-Johnson syndrome

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7
Q

The first step in establishing the occurence of adverse drug reaction is?

A

To classify the type of adverse reaction

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8
Q

What is a delayed adverse reaction to fertility drugs?

A

Ovarian cancer

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9
Q

Which antibiotics can give rise to drug fever?

A

Rifampicin

Carbamazepine

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10
Q

The most common form of dermatological manifestation of allergic drug reactions?

A

Morbiliform rash

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11
Q

A fatal result of drug-drug interaction of imidazoles and antihistamines is?

A

Torsades de pointes

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12
Q

What drugs shoud be avoided by patients with Brugada syndrome?

A

Amiodarone

Terfenadine

Azithromycin

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13
Q

The most common cause of adverse drug reactions in the last decade is due to?

A

Drug-drug interaction

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14
Q

Teratogenic effects are observed should women get pregnant within 2 years of taking this drug for acne?

A

Accutane(Isotretinoin)

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