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Pharmacology LU IV > Antiparasitics > Flashcards

Antiparasitics Flashcards

0
Q

True or false, metronidazole can penetrate the blood brain barrier?

A

True

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1
Q

What is the MOA of metronidazole?

A

DNA damage

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2
Q

What is the drug of choice for tetanus?

A

Metronidazole

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3
Q

What is the current Plasmodium falciparum drug-resistance in the Philippines?

A

Sensitive to artemether

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4
Q

What drugs are used for prophylaxis for malaria?

A

Mefloquine

Doxycyline

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5
Q

What is the current first line drug for Plasmodium falciparum in the Philippines?

A

Artemether-lumefantrine (Coartem)

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6
Q

What is the toxic effect of quinine?

A

Cinchonism

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7
Q

What is the current first line drug of choice for Plasmodium vivax in the Philippines?

A

Chloroquine

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8
Q

What is the only tissue schizonticide?

A

Primaquine

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9
Q

What is the drug of choice for filariasis?

A

Diethylcarbamazine (DEC)

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10
Q

What is the drug of choice for schistosomiasis?

A

Praziquantel

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11
Q

What is the drug of choice for paragonimiasis?

A

Praziquantel

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12
Q

What is the MOA of albendazole and mebendazole?

A

Inhibits microtubule synesis thus irreversibly impairing glucose uptake and ATP formation

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13
Q

What is the MOA of pyrantel embonate?

A

Stimulates nicotinic receptors at neuromuscular junctions causing increase contractions of muscles followed by depolarization inducing paralysis

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14
Q

What is the drug of choice for tape worms?

A

Praziquantel

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15
Q

What is the drug of choice for Ascaris and hookworms?

A

Albendazole

16
Q

What is the drug of choice for capillariasis?

A

Albendazole

17
Q

What is the drug of choice for Strongyloides sterocoralis?

A

Ivermectin

Pharmacology LU IV (12 decks)

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